AMH Mouse Monoclonal Antibody [Clone ID: 5/6]

CAT#: AM05878SU-N

AMH mouse monoclonal antibody, clone 5/6, Supernatant

Product Images

Immunohistochemistry: AM05878SU-N AMH antibody staining of Formalin Fixed Paraffin processed ovary tissue from a 25 day old Mouse.

Specifications

Product Data

• Clone Name: 5/6
• Applications: IHC, WB
• Recommended Dilution: Western blot.
  Immunohistology on Paraffin Sections: 1/20-1/40 (Requires antigen retrieval using heat treatment methods prior to staining, Sodium Citrate buffer pH 6.0 is recommended for this purpose).
  Recommended Positive Control: Ovary Tissue.
• Reactivities: Human, Monkey, Mouse, Sheep
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide derived from Human AMH.
  Spleen cells from immunised T/O outbred mice were fused with cells of the SP2/0 myeloma cell line
• Specificity: This antibody clone 5/6 is specific for Human anti-Mullerian Hormone (AMH), originally classified as a foetal testicular hormone that inhibits Mullerian duct development.
  AMH is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer.
• Formulation: State: Supernatant
  State: Liquid Concentrated Tissue Culture Supernatant
  Preservative: 0.09% Sodium Azide
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: anti-Mullerian hormone
• Database Link:
  Entrez Gene 268 Human
  UniProt ID P03971
• Background: Anti Mullerian Hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
• Synonyms: Muellerian-inhibiting factor, MIF, MIS