C3AR1 Mouse Monoclonal Antibody [Clone ID: hC3aRZ1]

CAT#: AM05568PU-N

C3AR1 mouse monoclonal antibody, clone hC3aRZ1, Purified

Specifications

Product Data

• Clone Name: hC3aRZ1
• Applications: FC, IHC
• Recommended Dilution: Immunohistochemistry on frozen sections.
  Flow Cytometry: 1/10 - 1/20.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human C3aR protein
• Specificity: This antibody recognises the receptor for complement component C3a (C3aR).
• Formulation: Phosphate buffered saline pH7.4 containing 0.09% Sodium Azide
  State: Purified
  State: Liquid purified IgG
• Concentration: lot specific
• Purification: Affinity chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: complement component 3a receptor 1
• Database Link:
  Entrez Gene 719 Human
  UniProt ID Q16581
• Background: C3a is a 55kD cell surface protein of the rhodopsin family of G protein-coupled seven-transmembrane receptors. C3a is an anaphylatoxin, which is a potent proinflammatory mediator that possesses immunoregulatory properties. C3a regulates inflammatory functions by binding to the C3a receptor. C3aR is expressed on various tissues and leucocytes including basophils, neutrophils, mast cells, eosinophils and activated T lymphocytes. Expression levels of C3aR on human cells varies significantly between donors.
• Synonyms: C3a-R, C3AR, C3AR1, AZ3B, C3R1, HNFAG09