Vaccinia Virus Mouse Monoclonal Antibody [Clone ID: B408M]

CAT#: AM05154PU-N

Vaccinia Virus mouse monoclonal antibody, clone B408M, Purified

Specifications

Product Data

• Clone Name: B408M
• Applications: ELISA, IF
• Recommended Dilution: ELISA.
  IFA.
  Immunohistochemisty.
  Lateral Flow.
• Reactivities: Vaccinia virus
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Native, intact Lister strain of Vaccinia virus.
• Specificity: This antibody recognizes free Vaccinia Virus and infected cells. Specific to the A33R protein.
  Reactive with Lister and NYCBH strains.
• Formulation: 0.01M PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction (> 90% pure)
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Protein A Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Background: Vaccinia virus is an Orthopoxvirus, containing double stranded DNA. Fusion protein plays an important role in the entry of enveloped virus into cells. As vaccinia virus has a wide host range, it is conceivable that certain cellular components that are ubiquitously expressed on the cell mediate virus infection. The study of the entry process, attachment, fusion and the proteins and receptors involved is complex. During vaccinia virus infection, the fusion process is attributed to the action of the 14KDa protein (A27L). The N terminus of this protein recognises heparan sulfate on the cell surface. It interacts with the negative charges of sulfates of glycosaminoglycans (GAGs).