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OriGene in recent publications
Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease Bioorg. Med. Chem. Lett. 2017 [ENGASE]

The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ Life Sci. 2017 [OLR1]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [HSPA5]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [ERN1]

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15445 TrueORF belong to family "druggable genome"

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SKUAccnSymbolDescriptionShipping
RC200019NM_015980HMP19HMP19 (Myc-DDK-tagged)-Human HMP19 protein (HMP19)Immediate
RC200021NM_016334GPR89BGPR89B (Myc-DDK-tagged)-Human G protein-coupled receptor 89B (GPR89B)Immediate
RC200045NM_139201GIT2GIT2 (Myc-DDK-tagged)-Human G protein-coupled receptor kinase interacting ArfGAP 2 (GIT2), transcript variant 4Immediate
RC200094NM_012242DKK1DKK1 (Myc-DDK-tagged)-Human dickkopf homolog 1 (Xenopus laevis) (DKK1)Immediate
RC200126NM_018207TRIM62TRIM62 (Myc-DDK-tagged)-Human tripartite motif containing 62 (TRIM62)Immediate
RC200156NM_175840SMOXSMOX (Myc-DDK-tagged)-Human spermine oxidase (SMOX), transcript variant 2Immediate
RC200244NM_014358CLEC4ECLEC4E (Myc-DDK-tagged)-Human C-type lectin domain family 4, member E (CLEC4E)Immediate
RC200294NM_032637SKP2SKP2 (Myc-DDK-tagged)-Human S-phase kinase-associated protein 2 (p45) (SKP2), transcript variant 23 week
RC200299NM_001003688SMAD1SMAD1 (Myc-DDK-tagged)-Human SMAD family member 1 (SMAD1), transcript variant 2Immediate
RC200304NM_002872RAC2RAC2 (Myc-DDK-tagged)-Human ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2)Immediate
RC200337NM_005151USP14USP14 (Myc-DDK-tagged)-Human ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (USP14), transcript variant 1Immediate
RC200340NM_004982KCNJ8KCNJ8 (Myc-DDK-tagged)-Human potassium inwardly-rectifying channel, subfamily J, member 8 (KCNJ8)Immediate
RC200351NM_004794RAB33ARAB33A (Myc-DDK-tagged)-Human RAB33A, member RAS oncogene family (RAB33A)Immediate
RC200358NM_004635MAPKAPK3MAPKAPK3 (Myc-DDK-tagged)-Human mitogen-activated protein kinase-activated protein kinase 3 (MAPKAPK3)Immediate
RC200376NM_004725BUB3BUB3 (Myc-DDK-tagged)-Human budding uninhibited by benzimidazoles 3 homolog (yeast) (BUB3), transcript variant 1Immediate
RC200402NM_139323YWHABYWHAB (Myc-DDK-tagged)-Human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (YWHAB), transcript variant 2Immediate
RC200423NM_001035258RPL38RPL38 (Myc-DDK-tagged)-Human ribosomal protein L38 (RPL38), transcript variant 2Immediate
RC200430NM_000964RARARARA (Myc-DDK-tagged)-Human retinoic acid receptor, alpha (RARA), transcript variant 1Immediate
RC200437NM_002801PSMB10PSMB10 (Myc-DDK-tagged)-Human proteasome (prosome, macropain) subunit, beta type, 10 (PSMB10)Immediate
RC200449NM_001004720NCK2NCK2 (Myc-DDK-tagged)-Human NCK adaptor protein 2 (NCK2), transcript variant 2Immediate

 

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