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HomeAll Cancer Mutant ClonesXRCC1 Mutants

Description of the mutations of XRCC1 (NM_006297) Mutants

Keys for Mutation Description

A.A. substitution
NT deletion
NT insertion
R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted


SKUMutation DescriptionAffected Codon#Affected NT#DescriptionEffect
RC402801 V72A72215T>CSinle srnd breks, ssoiion wih
RC402802 R194W194580C>TBenin bres disese, ssoiion wih
RC402803 R280H280839G>AInresed lun nerisk, ssoiion wih
RC402804 R399Q3991196G>AInresed lun nerisk, ssoiion wih


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