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HomeAll Cancer Mutant ClonesRB1 Mutants

Description of the mutations of RB1 (NM_000321) Mutants

Keys for Mutation Description

A.A. substitution
NT deletion
NT insertion
R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted


SKUMutation DescriptionAffected Codon#Affected NT#DescriptionEffect
RC400164 R556*556c.1666C>TTruncation
RC400166 R455*455c.1363C>TTruncation
RC400165 R661W661c.1981C>TMissense
RC400167 R552*552c.1654C>TTruncation
RC400168 R251*251c.751C>TTruncation


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