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HomeAll Cancer Mutant ClonesCDK4 Mutants

Description of the mutations of CDK4 (NM_000075) Mutants

Keys for Mutation Description

A.A. substitution
NT deletion
NT insertion
R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted


SKUMutation DescriptionAffected Codon#Affected NT#DescriptionEffect
RC401059 R24H2471G>AMelnom
RC401060 R24C2470C>TMelnom
RC401061 N41S41122A>GMelnom
RC401062 S52N52155G>AMelnom


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