CED6 (GULP1) Human Gene Knockout Kit (CRISPR)

CAT#: KN221580LP

GULP1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: CED6
• Locus ID: 51454
• Components:

  KN221580G1, CED6 gRNA vector 1 in pCas-Guide CRISPR vector

  KN221580G2, CED6 gRNA vector 2 in pCas-Guide CRISPR vector

  KN221580LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001252668, NM_001252669, NM_016315, NR_045562, NR_045563
• UniProt ID: Q9UBP9
• Synonyms: CED-6; CED6; GULP
• Summary: The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene. [provided by RefSeq, Nov 2011]