CD9 Human Gene Knockout Kit (CRISPR)

CAT#: KN202000BN

CD9 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Donor DNA: mBFP-Neo
• Symbol: CD9
• Locus ID: 928
• Components:

  KN202000G1, CD9 gRNA vector 1 in pCas-Guide CRISPR vector

  KN202000G2, CD9 gRNA vector 2 in pCas-Guide CRISPR vector

  KN202000BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001769, NM_001330312
• UniProt ID: P21926
• Synonyms: BTCC-1; DRAP-27; MIC3; MRP-1; TSPAN-29; TSPAN29
• Summary: This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]