Mouse Aldh4a1 activation kit by CRISPRa

CAT#: GA213096

Aldh4a1 CRISPRa kit - CRISPR gene activation of mouse aldehyde dehydrogenase 4 family, member A1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Aldh4a1
• Locus ID: 212647
• Kit Components:

  GA213096G1, Aldh4a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA213096G2, Aldh4a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA213096G3, Aldh4a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_175438
• UniProt ID: Q8CHT0
• Synonyms: A930035F14Rik; Ahd-1; Ahd1; Aldh4; Aldh5a1; E330022C09; P5cd; P5cdh; P5cdhl; P5cdhs; Ssdh1
• Summary: Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity).[UniProtKB/Swiss-Prot Function]