Mouse Dbr1 activation kit by CRISPRa

CAT#: GA211253

Dbr1 CRISPRa kit - CRISPR gene activation of mouse debranching RNA lariats 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Dbr1
• Locus ID: 83703
• Kit Components:

  GA211253G1, Dbr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA211253G2, Dbr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA211253G3, Dbr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_031403, NM_001368298
• UniProt ID: Q923B1
• Synonyms: AW018415
• Summary: Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity).[UniProtKB/Swiss-Prot Function]