Mouse Abcb5 activation kit by CRISPRa

CAT#: GA210808

Abcb5 CRISPRa kit - CRISPR gene activation of mouse ATP-binding cassette, sub-family B (MDR/TAP), member 5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Abcb5
• Locus ID: 77706
• Kit Components:

  GA210808G1, Abcb5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA210808G2, Abcb5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA210808G3, Abcb5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_029961
• UniProt ID: B5X0E4
• Synonyms: 9230106F14Rik
• Summary: Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.[UniProtKB/Swiss-Prot Function]