Mouse Ero1a activation kit by CRISPRa

CAT#: GA205326

Ero1l CRISPRa kit - CRISPR gene activation of mouse ERO1-like (S. cerevisiae)

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Ero1a
• Locus ID: 50527
• Kit Components:

  GA205326G1, Ero1a gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205326G2, Ero1a gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205326G3, Ero1a gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015774
• UniProt ID: Q8R180
• Synonyms: ERO1-L; Ero1a
• Summary: This gene encodes a member of the endoplasmic reticulum oxidoreductin family. The encoded protein is localized to the endoplasmic reticulum and promotes the formation of disulfide bonds by oxidizing protein disulfide isomerase. This gene may play a role in endoplasmic reticulum stress-induced apoptosis and the cellular response to hypoxia. [provided by RefSeq, Feb 2011]