Mouse Ccn4 activation kit by CRISPRa

CAT#: GA204628

Ccn4 CRISPRa kit - CRISPR gene activation of mouse cellular communication network factor 4

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Ccn4
• Locus ID: 22402
• Kit Components:

  GA204628G1, Ccn4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA204628G2, Ccn4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA204628G3, Ccn4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018865
• UniProt ID: O54775
• Synonyms: AW146261; CCN4; Elm1
• Summary: Downstream regulator in the Wnt/Frizzled-signaling pathway (By similarity). Associated with cell survival. Adheres to skin and melanoma fibroblasts (By similarity). In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan (By similarity). Suppresses tumor growth in vivo.[UniProtKB/Swiss-Prot Function]