Mouse Gli1 activation kit by CRISPRa

CAT#: GA201628

Gli1 CRISPRa kit - CRISPR gene activation of mouse GLI-Kruppel family member GLI1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Gli1
• Locus ID: 14632
• Kit Components:

  GA201628G1, Gli1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201628G2, Gli1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201628G3, Gli1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010296
• UniProt ID: P47806
• Synonyms: AV235269; Zfp-5; Zfp5
• Summary: Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal development. Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling. Plays a role in cell proliferation and differentiation via its role in SHH signaling.[UniProtKB/Swiss-Prot Function]