Mouse Egf activation kit by CRISPRa

CAT#: GA201197

Egf CRISPRa kit - CRISPR gene activation of mouse epidermal growth factor

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Egf
• Locus ID: 13645
• Kit Components:

  GA201197G1, Egf gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201197G2, Egf gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201197G3, Egf gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010113
• UniProt ID: P01132
• Synonyms: AI790464
• Summary: This gene encodes epidermal growth factor (EGF), the founding member of the EGF family of growth factors that are implicated in cell proliferation and differentiation. The encoded protein can localize to the membrane and function in juxtacrine signaling or undergo proteolytic processing to generate a soluble form of the hormone. Mice lacking the encoded protein do not exhibit an abnormal phenotype but transgenic mice overexpressing the encoded protein exhibit hypospermatogenesis. [provided by RefSeq, Jul 2016]