Mouse Bid activation kit by CRISPRa

CAT#: GA200407

Bid CRISPRa kit - CRISPR gene activation of mouse BH3 interacting domain death agonist

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Bid
• Locus ID: 12122
• Kit Components:

  GA200407G1, Bid gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA200407G2, Bid gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA200407G3, Bid gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007544
• UniProt ID: P70444
• Synonyms: 2700049M22Rik; AI875481; AU022477
• Summary: Induces caspases and apoptosis. Counters the protective effect of Bcl-2. The major proteolytic product p15 BID allows the release of cytochrome c.[UniProtKB/Swiss-Prot Function]