Human WNT5B activation kit by CRISPRa

CAT#: GA113012

WNT5B CRISPRa kit - CRISPR gene activation of human Wnt family member 5B

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: WNT5B
• Locus ID: 81029
• Kit Components:

  GA113012G1, WNT5B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA113012G2, WNT5B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA113012G3, WNT5B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_030775, NM_032642
• UniProt ID: Q9H1J7
• Synonyms: MGC2648
• Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]