Human Argonaute 2 (AGO2) activation kit by CRISPRa

CAT#: GA109045

AGO2 CRISPRa kit - CRISPR gene activation of human argonaute RISC catalytic component 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: AGO2
• Locus ID: 27161
• Kit Components:

  GA109045G1, Argonaute 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109045G2, Argonaute 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109045G3, Argonaute 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001164623, NM_012154
• UniProt ID: Q9UKV8
• Synonyms: EIF2C2; Q10
• Summary: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]