Human FADS2 activation kit by CRISPRa

CAT#: GA106285

FADS2 CRISPRa kit - CRISPR gene activation of human fatty acid desaturase 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: FADS2
• Locus ID: 9415
• Kit Components:

  GA106285G1, FADS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106285G2, FADS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106285G3, FADS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001281501, NM_001281502, NM_004265
• UniProt ID: O95864
• Synonyms: D6D; DES6; FADSD6; LLCDL2; SLL0262; TU13
• Summary: The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]