Human RAI3 (GPRC5A) activation kit by CRISPRa

CAT#: GA106019

GPRC5A CRISPRa kit - CRISPR gene activation of human G protein-coupled receptor class C group 5 member A

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: GPRC5A
• Locus ID: 9052
• Kit Components:

  GA106019G1, RAI3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106019G2, RAI3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106019G3, RAI3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003979
• UniProt ID: Q8NFJ5
• Synonyms: GPCR5A; PEIG-1; RAI3; RAIG1; TIG1
• Summary: This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. [provided by RefSeq, Jul 2008]