Human YY1 activation kit by CRISPRa

CAT#: GA105180

YY1 CRISPRa kit - CRISPR gene activation of human YY1 transcription factor

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: YY1
• Locus ID: 7528
• Kit Components:

  GA105180G1, YY1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105180G2, YY1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105180G3, YY1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003403
• UniProt ID: P25490
• Synonyms: DELTA; INO80S; NF-E1; UCRBP; YIN-YANG-1
• Summary: YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq, Jul 2008]