Human WNT7A activation kit by CRISPRa

CAT#: GA105152

WNT7A CRISPRa kit - CRISPR gene activation of human Wnt family member 7A

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: WNT7A
• Locus ID: 7476
• Kit Components:

  GA105152G1, WNT7A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105152G2, WNT7A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105152G3, WNT7A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004625
• UniProt ID: O00755
• Synonyms: AI849442; OTTMUSP00000024971; postaxial hemimelia; px; tw; wingless-related MMTV integration site 7A; Wnt-7a
• Summary: This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes. [provided by RefSeq, Jul 2008]