Human Glucose Transporter GLUT1 (SLC2A1) activation kit by CRISPRa

CAT#: GA104438

SLC2A1 CRISPRa kit - CRISPR gene activation of human solute carrier family 2 member 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SLC2A1
• Locus ID: 6513
• Kit Components:

  GA104438G1, Glucose Transporter GLUT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa, Target Sequence: AGTGCACCGAAGTCACCCAG

  GA104438G2, Glucose Transporter GLUT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa, Target Sequence: GCTGGACTGGAGTTCTCACT

  GA104438G3, Glucose Transporter GLUT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa, Target Sequence: CATTTTGCTAGAGAAGGCCG

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006516
• UniProt ID: P11166
• Synonyms: CSE; DYT9; DYT17; DYT18; EIG12; GLUT; GLUT-1; GLUT1; GLUT1DS; HTLVR; PED; SDCHCN
• Summary: This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Apr 2013]