Human SCD1 (SCD) activation kit by CRISPRa

CAT#: GA104287

SCD CRISPRa kit - CRISPR gene activation of human stearoyl-CoA desaturase

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SCD
• Locus ID: 6319
• Kit Components:

  GA104287G1, SCD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104287G2, SCD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104287G3, SCD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005063
• UniProt ID: O00767
• Synonyms: FADS5; hSCD1; MSTP008; SCD1; SCDOS
• Summary: This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015]