Human PRKACB activation kit by CRISPRa

CAT#: GA103759

PRKACB CRISPRa kit - CRISPR gene activation of human protein kinase cAMP-activated catalytic subunit beta

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PRKACB
• Locus ID: 5567
• Kit Components:

  GA103759G1, PRKACB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103759G2, PRKACB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103759G3, PRKACB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242857, NM_001242858, NM_001242859, NM_001242860, NM_001242861, NM_001242862, NM_001300915, NM_001300916, NM_001300917, NM_002731, NM_182948, NM_207578
• UniProt ID: P22694
• Synonyms: PKA C-beta; PKACB
• Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2014]