Human GATA4 activation kit by CRISPRa

CAT#: GA101747

GATA4 CRISPRa kit - CRISPR gene activation of human GATA binding protein 4

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: GATA4
• Locus ID: 2626
• Kit Components:

  GA101747G1, GATA4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101747G2, GATA4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101747G3, GATA4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001308093, NM_001308094, NM_002052
• UniProt ID: P43694
• Synonyms: ASD2; TACHD; TOF; VSD1
• Summary: This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]