Human hCG (CGA) activation kit by CRISPRa

CAT#: GA100777

CGA CRISPRa kit - CRISPR gene activation of human glycoprotein hormones, alpha polypeptide

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CGA
• Locus ID: 1081
• Kit Components:

  GA100777G1, hCG gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100777G2, hCG gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100777G3, hCG gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000735, NM_001252383
• UniProt ID: P01215
• Synonyms: CG-ALPHA; FSHA; GPHa; GPHA1; HCG; LHA; TSHA
• Summary: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]