Human CBR1 activation kit by CRISPRa

CAT#: GA100615

CBR1 CRISPRa kit - CRISPR gene activation of human carbonyl reductase 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CBR1
• Locus ID: 873
• Kit Components:

  GA100615G1, CBR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100615G2, CBR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100615G3, CBR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001286789, NM_001757, N51716
• UniProt ID: P16152
• Synonyms: CBR; hCBR1; SDR21C1
• Summary: The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013]