Human CAMK2B activation kit by CRISPRa

CAT#: GA100569

CAMK2B CRISPRa kit - CRISPR gene activation of human calcium/calmodulin dependent protein kinase II beta

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CAMK2B
• Locus ID: 816
• Kit Components:

  GA100569G1, CAMK2B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100569G2, CAMK2B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100569G3, CAMK2B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001220, NM_001293170, NM_172078, NM_172079, NM_172080, NM_172081, NM_172082, NM_172083, NM_172084
• UniProt ID: Q13554
• Synonyms: CAM2; CAMK2; CAMKB
• Summary: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]