Human ASCL2 activation kit by CRISPRa

CAT#: GA100311

ASCL2 CRISPRa kit - CRISPR gene activation of human achaete-scute family bHLH transcription factor 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ASCL2
• Locus ID: 430
• Kit Components:

  GA100311G1, ASCL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100311G2, ASCL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100311G3, ASCL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005170
• UniProt ID: Q99929
• Synonyms: ASH2; bHLHa45; HASH2; MASH2
• Summary: This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008]