Human Adenine Nucleotide Translocator 2 (SLC25A5) activation kit by CRISPRa

CAT#: GA100204

SLC25A5 CRISPRa kit - CRISPR gene activation of human solute carrier family 25 member 5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SLC25A5
• Locus ID: 292
• Kit Components:

  GA100204G1, Adenine Nucleotide Translocator 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100204G2, Adenine Nucleotide Translocator 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100204G3, Adenine Nucleotide Translocator 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001152
• UniProt ID: P05141
• Synonyms: 2F1; AAC2; ANT2; T2; T3
• Summary: This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]