Human beta Actin (ACTB) activation kit by CRISPRa

CAT#: GA100047

ACTB CRISPRa kit - CRISPR gene activation of human actin beta

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ACTB
• Locus ID: 60
• Kit Components:

  GA100047G1, beta Actin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100047G2, beta Actin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100047G3, beta Actin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001101
• UniProt ID: P60709
• Synonyms: BRWS1; PS1TP5BP1
• Summary: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. [provided by RefSeq, Aug 2017]