Prolactin Receptor (PRLR) (NM_000949) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209266L4V

Lenti ORF particles, PRLR (mGFP-tagged) - Human prolactin receptor (PRLR), transcript variant 1, 200ul, >10^7 TU/mL

Product Images

RC209266L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC209266L4V particle to overexpress human PRLR-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Prolactin Receptor
• Synonyms: HPRL; hPRLrI; MFAB; RI-PRLR
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_000949
• ORF Size: 1866 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209266).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000949.2
• RefSeq Size: 11694 bp
• RefSeq ORF: 1869 bp
• Locus ID: 5618
• UniProt ID: P16471
• Cytogenetics: 5p13.2
• Domains: FN3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction
• MW: 69.5 kDa
• Gene Summary: This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]