Actin (ACTA1) (NM_001100) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC203112L3V
- LentiORF®
Lenti ORF particles, ACTA1 (Myc-DDK-tagged)-Human actin, alpha 1, skeletal muscle (ACTA1), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
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USD 365.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | ACTA1 |
Synonyms | ACTA; ASMA; CFTD; CFTD1; CFTDM; MPFD; NEM1; NEM2; NEM3; SHPM |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001100 |
ORF Size | 1131 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC203112).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001100.3 |
RefSeq Size | 1509 bp |
RefSeq ORF | 1134 bp |
Locus ID | 58 |
UniProt ID | P68133 |
Cytogenetics | 1q42.13 |
Domains | ACTIN |
Protein Families | Stem cell - Pluripotency |
MW | 41.9 kDa |
Gene Summary | The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia. [provided by RefSeq, Sep 2019] |
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