TMEM147 (NM_032635) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200560L1V

Lenti ORF particles, TMEM147 (Myc-DDK tagged) - Human transmembrane protein 147 (TMEM147), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: TMEM147
• Synonyms: NIFIE14
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_032635
• ORF Size: 672 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200560).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_032635.2
• RefSeq Size: 909 bp
• RefSeq ORF: 675 bp
• Locus ID: 10430
• UniProt ID: Q9BVK8
• Cytogenetics: 19q13.12
• Protein Families: Druggable Genome, GPCR, Transmembrane
• MW: 25.3 kDa
• Gene Summary: Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (PubMed:21056967). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (PubMed:21056967).[UniProtKB/Swiss-Prot Function]