Bad (NM_007522) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR225008L4V

Lenti ORF particles, Bad (GFP-tagged) - Mouse BCL2-associated agonist of cell death (Bad), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Bad
• Synonyms: AI325008; Bbc2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_007522
• ORF Size: 615 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR225008).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007522.2, NP_031548.1
• RefSeq Size: 1458 bp
• RefSeq ORF: 615 bp
• Locus ID: 12015
• UniProt ID: Q61337
• Cytogenetics: 19 A
• Gene Summary: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.[UniProtKB/Swiss-Prot Function]