Ctnna2 (NM_145732) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR219148L4V

  • LentiORF®

Lenti ORF particles, Ctnna2 (GFP-tagged) - Mouse catenin (cadherin associated protein), alpha 2 (Ctnna2), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK w/ Puro mGFP w/ Puro



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USD 1,461.00

12 Weeks*

Size
    • 200 ul

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Specifications

Product Data
Type Mouse Tagged ORF Clone
Tag mGFP
Symbol Ctnna2
Synonyms AI481747; Catna; Catna2; cdf; chp
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_145732
ORF Size 2715 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR219148).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_145732.2, NP_663785.2
RefSeq Size 4004 bp
RefSeq ORF 2718 bp
Locus ID 12386
UniProt ID Q61301
Cytogenetics 6 33.54 cM
Gene Summary May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system (PubMed:12123610, PubMed:15034585). Required for proper regulation of cortical neuronal migration and neurite growth. It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization. It thereby suppresses excessive actin branching which would impair neurite growth and stability (By similarity). Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation (PubMed:12089526).[UniProtKB/Swiss-Prot Function]

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