Msh3 (NM_010829) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR218117L4V

Lenti ORF particles, Msh3 (GFP-tagged) - Mouse mutS homolog 3 (E. coli) (Msh3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Msh3
• Synonyms: D13Em1; Rep-3; Rep3
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_010829
• ORF Size: 3285 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR218117).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_010829.2, NP_034959.2
• RefSeq Size: 3945 bp
• RefSeq ORF: 3288 bp
• Locus ID: 17686
• UniProt ID: P13705
• Cytogenetics: 13 47.63 cM
• Gene Summary: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis (By similarity).[UniProtKB/Swiss-Prot Function]