Eif4e2 (NM_023314) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR216864L3V

Lenti ORF particles, Eif4e2 (Myc-DDK-tagged) - Mouse eukaryotic translation initiation factor 4E member 2 (Eif4e2), transcript variant 3, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Eif4e2
• Synonyms: 2700069E09Rik; AI036339; AV129531; D0H0S6743E; Eif4el3
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_023314
• ORF Size: 702 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR216864).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_023314.3, NP_075803.2
• RefSeq Size: 3394 bp
• RefSeq ORF: 705 bp
• Locus ID: 26987
• UniProt ID: Q8BMB3
• Cytogenetics: 1 C5
• Gene Summary: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:15153109). Acts as a repressor of translation initiation (By similarity). In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap (PubMed:15153109).[UniProtKB/Swiss-Prot Function]