Chemokine Receptor D6 (ACKR2) (NM_001296) Human Untagged Clone

CAT#: SC319238

CCBP2 (untagged)-Human chemokine binding protein 2 (CCBP2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Chemokine Receptor D6
• Synonyms: CCBP2; CCR9; CCR10; CMKBR9; D6; hD6
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001296.3 GGATCCTTTCTGGAATGGAGGTCTTATGAGCTGCTATTGAACACGGCAGAGCCTGTTGGT
  GACCTGCACACAGGAGCCCTCCAGTCAGTACTGATTGAATTACTCAAGGCTGCCTCTCTG
  CAAAGTTGAGCACTACAGGACGTCGGGACTGGGCATTTCCTTCCAACATGGCCGCCACTG
  CCTCTCCGCAGCCACTCGCCACTGAGGATGCCGATTCTGAGAATAGCAGCTTCTATTACT
  ATGACTACCTGGATGAAGTGGCCTTCATGCTCTGCAGGAAGGATGCAGTGGTGTCCTTTG
  GCAAAGTCTTCCTCCCAGTCTTCTATAGCCTGATTTTTGTGTTGGGCCTCAGCGGGAACC
  TCCTTCTTCTCATGGTCTTGCTCCGTTACGTGCCTCGCAGGCGGATGGTTGAGATCTATC
  TGCTGAATCTGGCCATCTCCAACCTTCTGTTTCTGGTGACACTGCCCTTCTGGGGCATCT
  CCGTGGCCTGGCATTGGGTCTTCGGGAGTTTCTTGTGCAAGATGGTGAGCACTCTTTATA
  CTATTAACTTTTACAGTGGCATCTTTTTCATTAGCTGCATGAGCCTGGACAAGTACCTGG
  AGATCGTTCATGCTCAGCCCTACCACAGGCTGAGGACCCGGGCCAAGAGCCTGCTCCTTG
  CTACCATAGTATGGGCTGTGTCCCTGGCCGTCTCCATCCCTGATATGGTCTTTGTACAGA
  CACATGAAAATCCCAAGGGTGTGTGGAACTGCCACGCAGATTTCGGCGGGCATGGGACCA
  TTTGGAAGCTCTTCCTCCGCTTCCAGCAGAACCTCCTAGGGTTTCTCCTTCCACTCCTTG
  CCATGATCTTCTTCTACTCCCGTATTGGTTGTGTCTTGGTGAGGCTGAGGCCCGCAGGCC
  AGGGCCGGGCTTTAAAAATAGCTGCAGCCTTGGTGGTGGCCTTCTTCGTGCTATGGTTCC
  CATACAATCTCACCTTGTTTCTGCATACGCTGTTGGACCTGCAAGTATTCGGGAACTGTG
  AGGTCAGCCAGCATCTAGACTACGCACTCCAGGTAACAGAGAGCATCGCCTTCCTTCACT
  GCTGCTTTTCCCCCATCCTGTATGCCTTCTCCAGTCACCGCTTCCGCCAGTACCTGAAGG
  CTTTCCTGGCTGCCGTGCTTGGATGGCACCTGGCACCTGGCACTGCCCAGGCCTCATTAT
  CCAGCTGTTCTGAGAGCAGCATACTTACTGCCCAAGAGGAAATGACTGGCATGAATGACC
  TTGGAGAGAGGCAGTCTGAGAACTACCCTAACAAGGAGGATGTGGGGAATAAATCAGCCT
  GAGTGACCAAATTTTGGTCTGGTGGGAACAGATGGGAACCAGCTCAATTGGGTGTCCACT
  CAAAGTGCTCTCTCCAGGGGCCTCAGTGACTGTGTTGCTAAACCCAGTGGTCAGTTCTCA
  GTTCTCAGCCATCAGCAGCATTTGCTCGCCCCGCCTTCTTCCTCCACTTTCTTCACTTGC
  TTCCAGGATACCACGCTTTCTTTTCTGAATTGCTACAATCTTTCTTCCTTCCTTCCTTGC
  TTCCTTCCTTCCTTCCTTCCCTCTCTCCCTCCCTCCCTCCCTCGCTTCTTCCCTTCCTCC
  TTTCCTCCCTTCCTACTTTCCTTCCTTCCTTCTGACAGGGTCTTGCTCTATTGCTCTGTC
  ACCCAGGCTGGAATGCAGTGGCGAGATCTCCGCTCACTGTAGCCTCCTCCCCCTGGGTTG
  AAGCAATTCTCATGCCTCAGCCTCCCAAGTAGCCAGGACTATAGGCACCTGCCACCATGC
  CTGGCTAATTTTTGTATTTTTTTTCTTTCTTTCTTTCTTTTCTTTTTTTTTTTTTTTTGA
  GACGGAGTCTCACTCTTGTTGCCCAGGCTGGACAACAATGGCGCGATCTCGGCTCACTGC
  AACCTCCACCTCCCGGATTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGAACT
  ACATGCGCGTGCCACCACGCACAGCTAATTTTTATAATTTTAGTAGAGATGGGGTTTCAC
  TGCGTTGGCCAGGATGATCTCGATCTCTTGACCTTGGGATCCACCCGCCTTGGCCTCCCA
  AAGTGCTGGGATTACAGGTGTGAGCCACCATGCCTGGCCCTAATTTTTGTGTTTTTATTA
  GAAACAGAGTTTCACCATGTTGGCCAGGCTGGAGAATTGCTGTAATAGTTTTCCAACTGG
  CCCCTGTCCTTCCTCTCTCTTGCTCTCCTCCCATCTCATCTGCACCTAGCAGCCAGAGTG
  ATCCTGATACTCTCGGCCTTTACTTCCGCCTCCCTCAGAGCAGCAGCCTGTCAAAACACC
  AGATTACAACAAATTTAGTTTAAAGGTCTCAATTAGCGTTATTGGCAATTCTAGAATCAG
  GCAACAGACTCATTGAATCAGGAACAGATTCACTCCATAAAATACAGAGAGTGCTGCAAT
  GAGCTGGGTAGAAGAGGTTAGTTTTATAGACAGGAAGGGGCTGTCAAAGGCAGAAAGAAA
  TGAAGAACAAAAAAAAAGATTGATTTTTTTTTTTTTGAGACAGGATCTCACTCTGTCATC
  CAGGCTGAAGTCCAATCCCACAATCATGGCTCACTGCAGCCACCACCTCCTGAGCTCAAG
  TGATCCTCCCATCTAAGCCCCCAAGTAGCTAGGACTACAGGAGCACACCACCACACCTGG
  CTAATTTTTGTATTTTTTGTGGAGACAGGGTCTCAGTATGTTACCCAGGTTGGACTGGAA
  ACCCTTGGCTCAAGCAATTTGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTG
  AGCCACTGCACAGGGCCAGATTCATCATTTCAAAGTTACTTTCTATATGCGGCCGGAACA
  GGGTGGTTGACATCAGTTTTCTTCAGGTTACTTTTTAATAATGATTAAAACGGGGAACTT
  CATTATCAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_001296
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001296.3, NP_001287.2
• RefSeq Size: 2962 bp
• RefSeq ORF: 1155 bp
• Locus ID: 1238
• UniProt ID: O00590
• Cytogenetics: 3p22.1
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Gene Summary: This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008]