ABCA5 (NM_172232) Human Untagged Clone

CAT#: SC306747

ABCA5 (untagged)-Human ATP-binding cassette, sub-family A (ABC1), member 5 (ABCA5), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ABCA5
• Synonyms: ABC13; EST90625; HTC3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_172232 edited
  GCCCACCATGTCCACTGCAATTAGGGAGGTAGGAGTTTGGAGACAGACCAGAACACTTCT
  ACTGAAGAATTACTTAATTAAATGCAGAACCAAAAAGAGTAGTGTTCAGGAAATTCTTTT
  TCCACTATTTTTTTTATTTTGGTTAATATTAATTAGCATGATGCATCCAAATAAGAAATA
  TGAAGAAGTGCCTAATATAGAACTCAATCCTATGGACAAGTTTACTCTTTCTAATCTAAT
  TCTTGGATATACTCCAGTGACTAATATTACAAGCAGCATCATGCAGAAAGTGTCTACTGA
  TCATCTACCTGATGTCATAATTACTGAAGAATATACAAATGAAAAAGAAATGTTAACATC
  CAGTCTCTCTAAGCCGAGCAACTTTGTAGGTGTGGTTTTCAAAGACTCCATGTCCTATGA
  ACTTCGTTTTTTTCCTGATATGATTCCAGTATCTTCTATTTATATGGATTCAAGAGCTGG
  CTGTTCAAAATCATGTGAGGCTGCTCAGTACTGGTCCTCAGGTTTCACAGTTTTACAAGC
  ATCCATAGATGCTGCCATTATACAGTTGAAGACCAATGTTTCTCTTTGGAAGGAGCTGGA
  GTCAACTAAAGCTGTTATTATGGGAGAAACTGCTGTTGTAGAAATAGATACCTTTCCCCG
  AGGAGTAATTTTAATATACCTAGTTATAGCATTTTCACCTTTTGGATACTTTTTGGCAAT
  TCATATCGTAGCAGAAAAAGAAAAAAAAATAAAAGAATTTTTAAAGATAATGGGACTTCA
  TGATACTGCCTTTTGGCTTTCCTGGGTTCTTCTATATACAAGTTTAATTTTTCTTATGTC
  CCTTCTTATGGCAGTCATTGCGACAGCTTCTTTGTTATTTCCTCAAAGTAGCAGCATTGT
  GATATTTCTGCTTTTTTTCCTTTATGGATTATCATCTGTATTTTTTGCTTTAATGCTGAC
  ACCTCTTTTTAAAAAATCAAAACATGTGGGAATAGTTGAATTTTTTGTTACTGTGGCTTT
  TGGATTTATTGGCCTTATGATAATCCTCATAGAAAGTTTTCCCAAATCGTTAGTGTGGCT
  TTTCAGTCCTTTCTGTCACTGTACTTTTGTGATTGGTATTGCACAGGTCATGCATTTAGA
  AGATTTTAATGAAGGTGCTTCATTTTCAAATTTGACTGCAGGCCCATATCCTCTAATTAT
  TACAATTATCATGCTCACACTTAATAGTATATTCTATGTCCTCTTGGCTGTCTATCTTGA
  TCAAGTCATTCCAGGGGAATTTGGCTTACGGAGATCATCTTTATATTTTCTGAAGCCTTC
  ATATTGGTCAAAGAGCAAAAGAAATTATGAGGAGTTATCAGAGGGCAATGTTAATGGAAA
  TATTAGTTTTAGTGAAATTATTGAGCCAGTTTCTTCAGAATTTGTAGGAAAAGAAGCCAT
  AAGAATTAGTGGTATTCAGAAGACATACAGAAAGAAGGGTGAAAATGTGGAGGCTTTGAG
  AAATTTGTCATTTGACATATATGAGGGTCAGATTACTGCCTTACTTGGCCACAGTGGAAC
  AGGAAAGAGTACATTGATGAATATTCTTTGTGGACTCTGCCCACCTTCTGATGGGTTTGC
  ATCTATATATGGACACAGAGTCTCAGAAATAGATGAAATGTTTGAAGCAAGAAAAATGAT
  TGGCATTTGTCCACAGTTAGATATACACTTTGATGTTTTGACAGTAGAAGAAAATTTATC
  AATTTTGGCTTCAATCAAAGGGATACCAGCCAACAATATAATACAAGAAGTGCAGAAGGT
  TTTACTAGATTTAGACATGCAGACTATCAAAGATAACCAAGCTAAAAAATTAAGTGGTGG
  TCAAAAAAGAAAGCTGTCATTAGGAATTGCTGTTCTTGGGAACCCAAAGATACTGCTGCT
  AGATGAACCAACAGCTGGAATGGACCCCTGTTCTCGACATATTGTATGGAATCTTTTAAA
  ATACAGAAAAGCCAATCGGGTGACAGTGTTCAGTACTCATTTCATGGATGAAGCTGACAT
  TCTTGCAGATAGGAAAGCTGTGATATCACAAGGAATGCTGAAATGTGTTGGTTCTTCAAT
  GTTCCTCAAAAGTAAATGGGGGATCGGCTACCGCCTGAGCATGTACATAGACAAATATTG
  TGCCACAGAATCTCTTTCTTCACTGGTTAAACAACATATACCTGGAGCTACTTTATTACA
  ACAGAATGACCAACAACTTGTGTATAGCTTGCCTTTCAAGGACATGGACAAATTTTCAGG
  TTTGTTTTCTGCCCTAGACAGTCATTCAAATTTGGGTGTCATTTCTTATGGTGTTTCCAT
  GACGACTTTGGAAGACGTATTTTTAAAGCTAGAAGTTGAAGCAGAAATTGACCAAGCAGA
  TTATAGTGTATTTACTCAGCAGCCACTGGAGGAAGAAATGGATTCAAAATCTTTTGATGA
  AATGGAACAGAGCTTACTTATTCTTTCTGAAACCAAGGCTGCTCTAGTGAGCACCATGAG
  CCTTTGGAAACAACAGATGTATACAATAGCAAAGTTTCATTTCTTTACCTTGAAACGTGA
  AAGTAAATCAGTGAGATCAGTGTTGCTTCTGCTTTTAATTTTTTTCACAGTTCAGATTTT
  TATGTTTTTGGTTCATCACTCTTTTAAAAATGCTGTGGTTCCCATCAAACTTGTTCCAGA
  CTTATATTTTCTAAAACCTGGAGACAAACCACATAAATACAAAACAAGTCTGCTTCTTCA
  AAATTCTGCTGACTCAGATATCAGTGATCTTATTAGCTTTTTCACAAGCCAGAACATAAT
  GGTGACGATGATTAATGACAGTGACTATGTATCCGTGGCTCCCCATAGTGCGGCTTTAAA
  TGTGATGCATTCAGAAAAGGACTATGTTTTTGCAGCTGTTTTCAACAGTACTATGGTTTA
  TTCTTTACCTATATTAGTGAATATCATTAGTAACTACTATCTTTATCATTTAAATGTGAC
  TGAAACCATCCAGATCTGGAGTACCCCATTCTTTCAAGAAATTACTGATATAGTTTTTAA
  AATTGAGCTGTATTTTCAAGCAGCTTTGCTTGGAATCATTGTTACTGCAATGCCACCTTA
  CTTTGCCATGGAAAATGCAGAGAATCATAAGATCAAAGCTTATACTCAACTTAAACTTTC
  AGGTCTTTTGCCATCTGCATATTGGATTGGACAAGCTGTTGTTGATATCCCCTTATTTTT
  TATCATTCTTATTTTGATGCTAGGAAGCTTATTGGCATTTCATTATGGATTATATTTTTA
  TACTGTAAAGTTCCTTGCTGTGGTTTTTTGCCTTATTGGTTATGTTCCATCAGTTATTCT
  GTTCACTTATATTGCTTCTTTCACCTTTAAGAAAATTTTAAATACCAAAGAATTTTGGTC
  ATTTATCTATTCTGTGGCAGCGTTGGCTTGTATTGCAATCACTGAAATAACTTTCTTTAT
  GGGATACACAATTGCAACTATTCTTCATTATGCCTTTTGTATCATCATTCCAATCTATCC
  ACTTCTAGGTTGCCTGATTTCTTTCATAAAGATTTCTTGGAAGAATGTACGAAAAAATGT
  GGACACCTATAATCCATGGGATAGGCTTTCAGTAGCTGTTATATCGCCTTACCTGCAGTG
  TGTACTGTGGATTTTCCTCTTACAATACTATGAGAAAAAATATGGAGGCAGATCAATAAG
  AAAAGATCCCTTTTTCAGAAACCTTTCAACGAAGTCTAAAAATAGGAAGCTTCCAGAACC
  ACCAGACAATGAGGATGAAGATGAAGATGTCAAAGCTGAAAGACTAAAGGTCAAAGAGCT
  GATGGGTTGCCAGTGTTGTGAGGAGAAACCATCCATTATGGTCAGCAATTTGCATAAAGA
  ATATGATGACAAGAAAGATTTTCTTCTTTCAAGAAAAGTAAAGAAAGTGGCAACTAAATA
  CATCTCTTTCTGTGTGAAAAAAGGAGAGATCTTAGGACTATTGGGTCCAAATGGTGCTGG
  CAAAAGCACAATTATTAATATTCTGGTTGGTGATATTGAACCAACTTCAGGCCAGGTATT
  TTTAGGAGATTATTCTTCAGAGACAAGTGAAGATGATGATTCACTGAAGTGTATGGGTTA
  CTGTCCTCAGATAAACCCTTTGTGGCCAGATACTACATTGCAGGAACATTTTGAAATTTA
  TGGAGCTGTCAAAGGAATGAGTGCAAGTGACATGAAAGAAGTCATAAGTCGAATAACACA
  TGCACTTGATTTAAAAGAACATCTTCAGAAGACTGTAAAGAAACTACCTGCAGGAATCAA
  ACGAAAGTTGTGTTTTGCTCTAAGTATGCTAGGGAATCCTCAGATTACTTTGCTAGATGA
  ACCATCTACAGGTATGGATCCCAAAGCCAAACAGCACATGTGGCGAGCAATTCGAACTGC
  ATTTAAAAACAGAAAGCGGGCTGCTATTCTGACCACTCACTATATGGAGGAGGCAGAGGC
  TGTCTGTGATCGAGTAGCTATCATGGTGTCTGGGCAGTTAAGATGTATCGGAACAGTACA
  ACATCTAAAGAGTAAATTTGGAAAAGGCTACTTTTTGGAAATTAAATTGAAGGACTGGAT
  AGAAAACCTAGAAGTAGACCGCCTTCAAAGAGAAATTCAGTATATTTTCCCAAATGCAAG
  CCGTCAGGAAAGTTTTTCTTCTATTTTGGCTTATAAAATTCCTAAGGAAGATGTTCAGTC
  CCTTTCACAATCTTTTTTTAAGCTGGAAGAAGCTAAACATGCTTTTGCCATTGAAGAATA
  TAGCTTTTCTCAAGCAACATTGGAACAGGTTTTTGTAGAACTCACTAAAGAACAAGAGGA
  GGAAGATAATAGTTGTGGAACTTTAAACAGCACACTTTGGTGGGAACGAACACAAGAAGA
  TAGAGTAGTATTTTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_172232
• Insert Size: 5000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_172232.1, NP_758424.1
• RefSeq Size: 5939 bp
• RefSeq ORF: 4929 bp
• Locus ID: 23461
• UniProt ID: Q8WWZ7
• Cytogenetics: 17q24.3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters
• Gene Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) represents the shorter transcript variant. It contains a distinct 5' UTR compared to transcript variant 1, but encodes the same protein. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments.