Casein Kinase 1 delta (CSNK1D) (NM_139062) Human Untagged Clone

CAT#: SC125335

CSNK1D (untagged)-Human casein kinase 1, delta (CSNK1D), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Casein Kinase 1 delta
• Synonyms: ASPS; CKI-delta; CKId; CKIdelta; FASPS2; HCKID
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_139062 edited
  ATGGAGCTGAGAGTCGGGAACAGGTACCGGCTGGGCCGGAAGATCGGCAGCGGCTCCTTC
  GGAGACATCTATCTCGGTACGGACATTGCTGCAGGAGAAGAGGTTGCCATCAAGCTTGAA
  TGTGTCAAAACCAAACACCCTCAGCTCCACATTGAGAGCAAAATCTACAAGATGATGCAG
  GGAGGAGTGGGCATCCCCACCATCAGATGGTGCGGGGCAGAGGGGGACTACAACGTCATG
  GTGATGGAGCTGCTGGGGCCAAGCCTGGAGGACCTCTTCAACTTCTGCTCCAGGAAATTC
  AGCCTCAAAACCGTCCTGCTGCTTGCTGACCAAATGATCAGTCGCATCGAATACATTCAT
  TCAAAGAACTTCATCCACCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAG
  AAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCAAGAAGTACCGGGATGCACGC
  ACCCACCAGCACATCCCCTATCGTGAGAACAAGAACCTCACGGGGACGGCGCGGTACGCC
  TCCATCAACACGCACCTTGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGC
  TACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGCAGGGGCTGAAGGCTGCCACC
  AAGAGACAGAAATACGAAAGGATTAGCGAGAAGAAAATGTCCACCCCCATCGAAGTGTTG
  TGTAAAGGCTACCCTTCCGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTT
  GACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCCGGAATCTGTTCCATCGCCAG
  GGCTTCTCCTATGACTACGTGTTCGACTGGAACATGCTCAAATTTGGTGCCAGCCGGGCC
  GCCGATGACGCCGAGCGGGAGCGCAGGGACCGAGAGGAGCGGCTGAGACACTCGCGGAAC
  CCGGCTACCCGCGGCCTCCCTTCCACAGCCTCCGGCCGCCTGCGGGGGACGCAGGAAGTG
  GCTCCCCCCACACCCCTCACCCCTACCTCACACACGGCTAACACCTCCCCCCGGCCCGTC
  TCCGGCATGGAGAGAGAGCGGAAAGTGAGTATGCGGCTGCACCGCGGGGCCCCCGTCAAC
  ATCTCCTCGTCCGACCTCACAGGCCGACAAGATACCTCTCGCATGTCCACCTCACAGAAT
  AGCATTCCTTTCGAACACCACGGCAAGTAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_139062 unedited
  NNNGGTTCACAATTGTATACGACTCACTATAGGCGGCCGCGAATCGGCACGAGGCGGCTC
  CTTTAGCAGCTGAAAGGGATTTAGGCCCGGAAGATCCGAGTCCATCCGCGGCGGGGAGAG
  GGCAAGCGGGACCGGTAGGGGCCGGAGCAGCGGCGGCGGCGCTCGGACTGTCCCATCCGC
  CCCGTATTGAGGCGCTGGGAGCGGCGGGGCGACAGGAAAGCGATGGTGAAAGCGGGGCCG
  TGAGGGGGGCGGAGCCGGGAGCCGGACCCGCAGTAGCGGCAGCAGCGGCGCCGCCTCCCA
  GAGTTCAGACCCAGGAAGCGGCCGGGAGGGCAGGAGCGAATCGGGCCGCCGCCGCCATGG
  AGCTGAGAGTCGGGAACAGGTACCGGCTGGGCCGGAAGATCGGCAGCGGCTCCTTCGGAG
  ACATCTATCTCGGTACGGACATTGCTGCAGGAGAAGAGGTTGCCATCAAGCTTGAATGTG
  TCAAAACCAAACACCCTCAGCTCCACATTGAGAGCAAAATCTACAAGATGATGCAGGGAG
  GAGTGGGCATCCCCACCATCAGATGGTGCNGGGCAGAGGGGGACTACAACGTCATGGTGA
  TGGAGCTGCTNGGGCCAAGCCTGGAGGACCTCTTCAACTTCTGCTCCAGGAAATTCAGCC
  TCAAAACCGTNCTGCTGCTTGCTGACCAAATGATCAGTCGCATCGAATACATTCATTCAA
  AGAACTTCATCCACCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGNNGGAAGAAG
  GNCAACCTGNTGTACATCATCGACTTCGGNCTGGNCAAAGAATACCGGNATGCACGCACC
  CACAGCACATNCNCTATCGTGAGACAAGAACTNCNGGGACNGNNGCGTACGCTNCATCAC
  ACGACCTTGGAAATGACATA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_139062 unedited
  TCNCGCAAATTACTGTGNACCGCGGCCGTATNCTANGACTCGNGTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTCAAATTTAAGCCAATAATTTTTAGCAAAATGATACAAAACT
  GTCTTAACCAAGTAAAAAATTGGTAGTTACAGTGGAATCGTCAGGGAGTACAGGGCGGCC
  ACCACTGGAGGGAGCTGAGGCCCTGGAAAAGGAGTCTGATTCTCTGCAATTCTCTCTCTG
  CTTTTCTTCCCAGCCCCGTTACAACCGAGTTCACGTGGGGGGCCGCAGTGCAGCCCCAGC
  GGTGGCAGCTCTTGGAGTCTGTCCGTTTAGTATGTTTCCCCCACAAGCGTCGCTGGGTGA
  GTGGCCTGGAAAGCTCCCGGTGTTAACATTTCGATCCTAGACCGGGGGACGTGTCACTAG
  TAAAGCCATTGGTAACAGAGTAAATCAGCCATGCATTGTCTGCCCTTCACAGCAATAAGG
  AGAGTTCTCATCGGTGCACGACAGACTGAAGACCACTGGAAGCCACCCGACCAGGAATCC
  AGTGCTGCCTTCCGATGGGAGACGAGCAGCTACTTGCCGTGGTGTTCGAAAGGAATGCTA
  TTCTGTGAGGTGGACATGCGAGAGGTATCTTGTCGGCCTGTGAGGTCGGACGAGGAGATG
  TTGACGGGGGCCCCGCGGTGCAGCCGCATACTCACTTTCCGCTCTCTCTCCATGCCGGAG
  ACGGGCCGGGGGGGAGGTGTTAACCNTGTGTGAGTAGGGTAGGGGTTTTTTTTNNNNNNT
  AACTNTTTTTTTGTGCTCCCCCCGCAGGCNGGCCGGGCCCTTNTNCAAGGAACGCCCCCG
  GTCNCCCGGCTTCCGCCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_139062
• Insert Size: 2500 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_139062.1, NP_620693.1
• RefSeq Size: 2106 bp
• RefSeq ORF: 1230 bp
• Locus ID: 1453
• UniProt ID: P48730
• Cytogenetics: 17q25.3
• Domains: pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Circadian rhythm - mammal, Gap junction, Hedgehog signaling pathway
• Gene Summary: This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
  Transcript Variant: This variant (2) has an additional exon at the 3' end compared to transcript variant 1. This results in a shorter isoform (2) with a different C-terminus compared to isoform 1.