cIAP2 (BIRC3) (NM_182962) Human Untagged Clone

CAT#: SC124623

BIRC3 (untagged)-Human baculoviral IAP repeat containing 3 (BIRC3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: cIAP2
• Synonyms: AIP1; API2; c-IAP2; CIAP2; HAIP1; HIAP1; IAP-1; MALT2; MIHC; RNF49
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_182962, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAACATAGTAGAAAACAGCATATTCTTATCAAATTTGATGAAAAGCGCCAACACGTTTGAACTGAAAT
  ACGACTTGTCATGTGAACTGTACCGAATGTCTACGTATTCCACTTTTCCTGCTGGGGTTCCTGTCTCAGA
  AAGGAGTCTTGCTCGTGCTGGTTTCTATTACACTGGTGTGAATGACAAGGTCAAATGCTTCTGTTGTGGC
  CTGATGCTGGATAACTGGAAAAGAGGAGACAGTCCTACTGAAAAGCATAAAAAGTTGTATCCTAGCTGCA
  GATTCGTTCAGAGTCTAAATTCCGTTAACAACTTGGAAGCTACCTCTCAGCCTACTTTTCCTTCTTCAGT
  AACAAATTCCACACACTCATTACTTCCGGGTACAGAAAACAGTGGATATTTCCGTGGCTCTTATTCAAAC
  TCTCCATCAAATCCTGTAAACTCCAGAGCAAATCAAGATTTTTCTGCCTTGATGAGAAGTTCCTACCACT
  GTGCAATGAATAACGAAAATGCCAGATTACTTACTTTTCAGACATGGCCATTGACTTTTCTGTCGCCAAC
  AGATCTGGCAAAAGCAGGCTTTTACTACATAGGACCTGGAGACAGAGTGGCTTGCTTTGCCTGTGGTGGA
  AAATTGAGCAATTGGGAACCGAAGGATAATGCTATGTCAGAACACCTGAGACATTTTCCCAAATGCCCAT
  TTATAGAAAATCAGCTTCAAGACACTTCAAGATACACAGTTTCTAATCTGAGCATGCAGACACATGCAGC
  CCGCTTTAAAACATTCTTTAACTGGCCCTCTAGTGTTCTAGTTAATCCTGAGCAGCTTGCAAGTGCGGGT
  TTTTATTATGTGGGTAACAGTGATGATGTCAAATGCTTTTGCTGTGATGGTGGACTCAGGTGTTGGGAAT
  CTGGAGATGATCCATGGGTTCAACATGCCAAGTGGTTTCCAAGGTGTGAGTACTTGATAAGAATTAAAGG
  ACAGGAGTTCATCCGTCAAGTTCAAGCCAGTTACCCTCATCTACTTGAACAGCTGCTATCCACATCAGAC
  AGCCCAGGAGATGAAAATGCAGAGTCATCAATTATCCATTTTGAACCTGGAGAAGACCATTCAGAAGATG
  CAATCATGATGAATACTCCTGTGATTAATGCTGCCGTGGAAATGGGCTTTAGTAGAAGCCTGGTAAAACA
  GACAGTTCAGAGAAAAATCCTAGCAACTGGAGAGAATTATAGACTAGTCAATGATCTTGTGTTAGACTTA
  CTCAATGCAGAAGATGAAATAAGGGAAGAGGAGAGAGAAAGAGCAACTGAGGAAAAAGAATCAAATGATT
  TATTATTAATCCGGAAGAATAGAATGGCACTTTTTCAACATTTGACTTGTGTAATTCCAATCCTGGATAG
  TCTACTAACTGCCGGAATTATTAATGAACAAGAACATGATGTTATTAAACAGAAGACACAGACGTCTTTA
  CAAGCAAGAGAACTGATTGATACGATTTTAGTAAAAGGAAATATTGCAGCCACTGTATTCAGAAACTCTC
  TGCAAGAAGCTGAAGCTGTGTTATATGAGCATTTATTTGTGCAACAGGACATAAAATATATTCCCACAGA
  AGATGTTTCAGATCTACCAGTGGAAGAACAATTGCGGAGACTACAAGAAGAAAGAACATGTAAAGTGTGT
  ATGGACAAAGAAGTGTCCATAGTGTTTATTCCTTGTGGTCATCTAGTAGTATGCAAAGATTGTGCTCCTT
  CTTTAAGAAAGTGTCCTATTTGTAGGAGTACAATCAAGGGTACAGTTCGTACATTTCTTTCATGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_182962 unedited
  TAGGATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCAAAGGTG
  CAATTGTGTATTTCTTCCTTAAAATGTATCAGTATAGGATTTAGAATCTCCATGTTGAAA
  CTCTAAATGCATAGAAATAAAAATAATAAAAAATTTTTCATTTTGGCTTTTCAGCCTAGT
  ATTAAAACTGATAAAAGCAAAGCCATGCACAAAACTACCTCCCTAGAGAAAGGCTAGTCC
  CTTTTCTTCCCCATTCATTTCATTATGAACATAGTAGAAAACAGCATATTCTTATCAAAT
  TTGATGAAAAGCGCCAACACGTTTGAACTGAAATACGACTTGTCATGTGAACTGTACCGA
  ATGTCTACGTATTCCACTTTTCCTGCTGGGGTTCCTGTCTCAAAAGGAGTCTTGCTCGTG
  CTGGTTTCTATTACACTGGGTGTGAATGACAAGGTCAAATGCTTCTGTTGTGGCCTGATG
  CTGAATAACTGGAAAAGAGGAGACAGTCCTACTGAAAAGATAAAAAGTGGGATCCTAACT
  GGAAAATTCGTCAGAAGTCTAATTCCCGTAACAACTTGGAAGGCAACCTTTCCACCCTAC
  TTTTTCCTTTTTACAGAAACAATTCCCCACACTTCTTTATTTCCGGGGACAAAAAAAAGA
  GGGAATTTTCCCGGGGCTTCTATTCAAACTCTCCTCAAAACCGGAAAACCCCAAAACAAA
  CAAAATTTTTCTGCCTGGAAAAAAAACCCTCCCCCGGGCCTTGAAAAAAAAAAAGGCCAA
  ATTCTTTTTTTTAAAATGGGCCTTTGTCTTTTTGTTCCACAAAAAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_182962 unedited
  GGGGGGGGNNGTTTTTNNNNANTTTTACTTGCCACGCGCCGCATACCGAGACCGNGTTTT
  TTTTTTTTTTTTTTAAATTTTGTTGCTTTTATAATTTTTTCTCACAAAATTCTTTTAAAA
  ACCCTGTCCCTAAATGTCTTCACTTTCCCCTTCTTATAGCCGTCAAAAAAACAATGTCCC
  TGGGTTGTTTGTCTGTGTTAAAGGCGCTATTGCTCCCGAGGATTCAAACTCCTGCTCAAT
  TTCTCTCCTCACCTGACTCGCCTCCCCCCCTGCTTCTTCCCGGTTTCATGCCAAATTAAA
  ATTCTAAAGTACTCATTCTATTTACTTCCTTACATTCATTGCTAATTATGATTTGGTTGA
  TGCTACCTTTTCTCTAAACAAACCTCTTCCTATTCTAAATTGTCTTGGTAATCTATTATT
  GTACCAACATGTTTGATTGAATATAAATTAAGAACCATTGTAAATTAAGTTATCCTTATA
  ATAATCTAGTTAACATGTTGT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_182962
• Insert Size: 2740 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_182962.1, NP_892007.1
• RefSeq Size: 2683 bp
• RefSeq ORF: 1815 bp
• Locus ID: 330
• UniProt ID: Q13489
• Cytogenetics: 11q22.2
• Protein Families: Druggable Genome
• Protein Pathways: Apoptosis, Focal adhesion, NOD-like receptor signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.