CD26 (DPP4) (NM_001935) Human Untagged Clone

CAT#: SC118956

DPP4 (untagged)-Human dipeptidyl-peptidase 4 (DPP4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CD26
• Synonyms: ADABP; ADCP2; CD26; DPPIV; TP103
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001935 edited
  GAATTCGGCACGAGGGCGAGTGACTCCACCGCCCGGAGCAGCGGTGCAGGACGCGCGTCT
  CCGCCGCCCGCGGTGACTTCTGCCTGCGCTCCTTCTCTGAACGCTCACTTCCGAGGAGAC
  GCCGACGATGAAGACACCGTGGAAGGTTCTTCTGGGACTGCTGGGTGCTGCTGCGCTTGT
  CACCATCATCACCGTGCCCGTGGTTCTGCTGAACAAAGGCACAGATGATGCTACAGCTGA
  CAGTCGCAAAACTTACACTCTAACTGATTACTTAAAAAATACTTATAGACTGAAGTTATA
  CTCCTTAAGATGGATTTCAGATCATGAATATCTCTACAAACAAGAAAATAATATCTTGGT
  ATTCAATGCTGAATATGGAAACAGCTCAGTTTTCTTGGAGAACAGTACATTTGATGAGTT
  TGGACATTCTATCAATGATTATTCAATATCTCCTGATGGGCAGTTTATTCTCTTAGAATA
  CAACTACGTGAAGCAATGGAGGCATTCCTACACAGCTTCATATGACATTTATGATTTAAA
  TAAAAGGCAGCTGATTACAGAAGAGAGGATTCCAAACAACACACAGTGGGTCACATGGTC
  ACCAGTGGGTCATAAATTGGCATATGTTTGGAACAATGACATTTATGTTAAAATTGAACC
  AAATTTACCAAGTTACAGAATCACATGGACGGGGAAAGAAGATATAATATATAATGGAAT
  AACTGACTGGGTTTATGAAGAGGAAGTCTTCAGTGCCTACTCTGCTCTGTGGTGGTCTCC
  AAACGGCACTTTTTTAGCATATGCCCAATTTAACGACACAGAAGTCCCACTTATTGAATA
  CTCCTTCTACTCTGATGAGTCACTGCAGTACCCAAAGACTGTACGGGTTCCATATCCAAA
  GGCAGGAGCTGTGAATCCAACTGTAAAGTTCTTTGTTGTAAATACAGACTCTCTCAGCTC
  AGTCACCAATGCAACTTCCATACAAATCACTGCTCCTGCTTCTATGTTGATAGGGGATCA
  CTACTTGTGTGATGTGACATGGGCAACACAAGAAAGAATTTCTTTGCAGTGGCTCAGGAG
  GATTCAGAACTATTCGGTCATGGATATTTGTGACTATGATGAATCCAGTGGAAGATGGAA
  CTGCTTAGTGGCACGGCAACACATTGAAATGAGTACTACTGGCTGGGTTGGAAGATTTAG
  GCCTTCAGAACCTCATTTTACCCTTGATGGTAATAGCTTCTACAAGATCATCAGCAATGA
  AGAAGGTTACAGACACATTTGCTATTTCCAAATAGATAAAAAAGACTGCACATTTATTAC
  AAAAGGCACCTGGGAAGTCATCGGGATAGAAGCTCTAACCAGTGATTATCTATACTACAT
  TAGTAATGAATATAAAGGAATGCCAGGAGGAAGGAATCTTTATAAAATCCAACTTAGTGA
  CTATACAAAAGTGACATGCCTCAGTTGTGAGCTGAATCCGGAAAGGTGTCAGTACTATTC
  TGTGTCATTCAGTAAAGAGGCGAAGTATTATCAGCTGAGATGTTCCGGTCCTGGTCTGCC
  CCTCTATACTCTACACAGCAGCGTGAATGATAAAGGGCTGAGAGTCCTGGAAGACAATTC
  AGCTTTGGATAAAATGCTGCAGAATGTCCAGATGCCCTCCAAAAAACTGGACTTCATTAT
  TTTGAATGAAACAAAATTTTGGTATCAGATGATCTTGCCTCCTCATTTTGATAAATCCAA
  GAAATATCCTCTACTATTAGATGTGTATGCAGGCCCATGTAGTCAAAAAGCAGACACTGT
  CTTCAGACTGAACTGGGCCACTTACCTTGCAAGCACAGAAAACATTATAGTAGCTAGCTT
  TGATGGCAGAGGAAGTGGTTACCAAGGAGATAAGATCATGCATGCAATCAACAGAAGACT
  GGGAACATTTGAAGTTGAAGATCAAATTGAAGCAGCCAGACAATTTTCAAAAATGGGATT
  TGTGGACAACAAACGAATTGCAATTTGGGGCTGGTCATATGGAGGGTACGTAACCTCAAT
  GGTCCTGGGATCGGGAAGTGGCGTGTTCAAGTGTGGAATAGCCGTGGCGCCTGTATCCCG
  GTGGGAGTACTATGACTCAGTGTACACAGAACGTTACATGGGTCTCCCAACTCCAGAAGA
  CAACCTTGACCATTACAGAAATTCAACAGTCATGAGCAGAGCTGAAAATTTTAAACAAGT
  TGAGTACCTCCTTATTCATGGAACAGCAGATGATAACGTTCACTTTCAGCAGTCAGCTCA
  GATCTCCAAAGCCCTGGTCGATGTTGGAGTGGATTTCCAGGCAATGTGGTATACTGATGA
  AGACCATGGAATAGCTAGCAGCACAGCACACCAACATATATATACCCACATGAGCCACTT
  CATAAAACAATGTTTCTCTTTACCTTAGCACCTCAAAATACCATGCCATTTAAAGCTTAT
  TAAAACTCATTTTTGTTTTCATTATCTCAAAACTGCACTGTCAAGATGATGATGATCTTT
  AAAATACACACTCAAATCAAGAAACTTAAGGTTACCTTTGTTCCCAAATTTCATACCTAT
  CATCTTAAGTAGGGACTTCTGTCTTCACAACAGATTATTACCTTACAGAAGTTTGAATTA
  TCCGGTCGGGTTTTATTGTTTAAAATCATTTCTGCATCAGCTGCTGAAACAACAAATAGG
  AATTGTTTTTATGGAGGCTTTGCATAGATTCCCTGAGCAGGATTTTAATCXXXXXXXXXX
  XXXXXXXXXXXXXXXGGTGGGGCAGTGATGTCACTTAGGGCAGGGACAGGATAAGAGGGA
  TTAGGGAGAGAAGATAGCAGGGCATGGCTGGGAACCCAAGTCCAAGCATACCAACACGAG
  CAGGCTACTGTCAGCTCCCCTCGGAGAAGAGCTGTTCACAGCCAGACTGGCACAGTTTTC
  TGAGAAAGACTATTCAAACAGTCTCAGGAAATCAAATATGCAAAGCACTGACTTCTAAGT
  AAAACCACAGCAGTTGAAAAGACTCCAAAGAAATGTAAGGGAAACTGCCAGCAACGCAGG
  CCCCCAGGTGCCAGTTATGGCTATAGGTGCTACAAAAACACAGCAAGGGTGATGGGAAAG
  CATTGTAAATGTGCTTTTAAAAAAAAATACTGATGTTCCTAGTGAAAGAGGCAGCTTGAA
  ACTGAGATGTGAACACATCAGCTTGCCCTGTTAAAAGATGAAAATATTTGTATCACAAAT
  CTTAACTTGAAGGAGTCCTTGCATCAATTTTTCTTATTTCATTTCTTTGAGTGTCTTAAT
  TAAAAGAATATTTTAACTTCCTTGGACTCATTTTAAAAAATGGAACATAAAATACAATGT
  TATGTATTATTATTCCCATTCTACATACTATGGAATTTCTCCCAGTCATTTAATAAATGT
  GCCTTCATTTTTTCAGAAGAAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001935 unedited
  GGGTGTCGGATTTTGTATACGACTCCTATGGGCGGCCCGCGATTCGGCACGAGGGCGAGT
  GACTCCACCGCCCGGNGCAGCGGTGCAGGACGCGCGTCTCCGCCGCCCGCGGTGACTTCT
  GCCTGCGCTCCTTCTCTGAACGCTCACTTCCGAGGAGACGCCGACGATGAAGACACCGTG
  GAAGGTTCTTCTGGGACTGCTGGGTGCTGCTGCGCTTGTCACCATCATCACCGTGCCCGT
  GGTTCTGCTGAACAAAGGCACAGATGATGCTACAGCTGACAGTCGCAAAACTTACACTCT
  AACTGATTACTTAAAAAATACTTATAGACTGAAGTTATACTCCTTAAGATGGATTTCAGA
  TCATGAATATCTCTACAAACAAGAAAATAATATCTTGGTATTCAATGCTGAATATGGAAA
  CAGCTCAGTTTTCTTGGAGAACAGTACATTTGATGAGTTTGGACATTCTATCAATGATTA
  TTCAATATCTCCTGATGGGCAGTTTATTCTCTTAGAATACAACTACGTGAAGCAATGGAG
  GCATTCCTACACAGCTTCATATGACATTTATGATTTAAATAAAAGGCAGCTGATTACAGA
  AGAGAGGATTCCAAACAACACACAGTGGGTCACATGGTCACCAGTGGGTCATAAATTGGC
  ATATGTTTGGAACAATGACATTTATGTTAAAATTGAACCAAATTTACCAAGTTACAGAAT
  CACATGGACGGNGAAAGAAGATATAATATATAATGGAATAACTGACTGGGTTTATGAANA
  GGGAAGTCTCAGTGCCTACTCTGCTCTGTGGGTGGTCTCCAACGGCACTNTNTTAGCATA
  TGCCCCATTTAACGACACAGAAAGTCCCACTTATTGATACTNCTTCTACTCTGATGAGTC
  ACTGCAGTACCAAGACTGTGTACGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001935 unedited
  GAACCGCGGGCCGCAATTTACAGTCGAGTTTTTTTTTTTTTTTTTTTCTTCTGAAAAATG
  ATGGCACATTTATTAAATGACTGGGAGAAATTCCATAGTATGTAGAATGGGAATAATAAT
  ACATAACATTGTATTTTATGTTCCATTTTTTAAAATGAGTCCAAGGAAGTTAAAATATTC
  TTTTAATTAAGACACTCAAAGAAATGAAATAAGAAAATTTGATGCAAGGACTCCTTCAAG
  TTAAGATTTGTGATACAATTTTTTTCATCTTTTAACAGGGCAAGCTGATGTGTTCACATC
  TCAGTTTCAAGCTGCCTCTTTCACTAGGAACATCAGTATTTTTTTTTAAAAGCACATTTA
  CAATGCTTTCCCATCACCCTTGCTGTGTTTTTGTAGCACCTATAGCCATAACTGGCACCT
  GGGGGCCTGCGTTGCTGGCAGTTTCCCTTACATTTCTTTGGAGTCTTTTCACCTGCTGTG
  GTTTTACTTACAAGTCAGTGCTTTGCATATTTGATTTCCTGAGACTGTTTGAATAGTCTT
  TCTCAGAAAACTGTGCCAGTCTGGCTGTGAAACAGCTCTTCTCCGAGGGGAGCTGACAGC
  CCCCTGCTCGTGTTGGTATGCCTGGACCTGGGTTACCAGACATGGCCTGCTATTTTCTTT
  CCTAATCCCTCCTACCCTGGCCCTGCCCTCATGACCCCCCTGCTCCCCCCCTTCCCCCCC
  TTCCAAAGAACACACCCCCTTCTGACCCCCTTCACCCTACCCCCCCCTACACCTCCTCCT
  TCGTAACTATATCCCTACCCTCCCTCCCCCCATCCTCCCTTCGCCCCCATCACTCCAGCC
  TCCCGCCCTTATCCCATTCCCCCTCCTGTTCTCCCCCCCCCCCCCAGCCCCCACCTCCCC
  TCGACACCTTATTCTCACCAATACCTCCCCCCCACTTCGTCCACCCGTCTTGCTTATATT
  CATCCTCCCCCTTCTCTCCCCCTCCTTATTTTACCCCCCCCCCCTCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001935
• Insert Size: 2301 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001935.3, NP_001926.2
• RefSeq Size: 3913 bp
• RefSeq ORF: 2301 bp
• Locus ID: 1803
• UniProt ID: P27487
• Cytogenetics: 2q24.2
• Domains: Peptidase_S9, DPPIV_N_term
• Protein Families: Druggable Genome, Protease, Secreted Protein, Transmembrane
• Gene Summary: The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19. [provided by RefSeq, Apr 2020]