SENP2 (NM_021627) Human Untagged Clone

CAT#: SC112903

SENP2 (untagged)-Human SUMO1/sentrin/SMT3 specific peptidase 2 (SENP2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SENP2
• Synonyms: AXAM2; SMT3IP2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112903 sequence for NM_021627 edited (data generated by NextGen Sequencing)
  ATGTACAGATGGCTGGTTAGGATTCTCGGCACCATTTTCCGTTTCTGCGACCGGTCGGTG
  CCCCCTGCCCGGGCCCTCCTGAAGAGGCGGCGCTCAGACAGCACTCTGTTTTCTACAGTG
  GACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAA
  AACAGTCTCTACAATGCTGCCAGCTTATTTGGATTCCCATTCCAGCTGACCACAAAGCCC
  ATGGTAACTTCTGCTTGTAATGGAACACGGAATGTGGCCCCTTCAGGAGAGGTATTTTCG
  AACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGGT
  AATAAATCTCCTAATGGAATAAGTGACTATCCAAAGATCAGAGTGACAGTTACCCGAGAT
  CAGCCACGCAGAGTCCTGCCTTCCTTTGGTTTTACTTTGAACTCAGAAGGCTGTAATAGA
  AGACCAGGTGGCCGTCGCCATAGCAAAGGTAATCCAGAGAGTTCTTTAATGTGGAAACCT
  CAGGAACAGGCTGTAACAGAGATGATTTCTGAAGAGAGTGGCAAGGGTCTGAGGCGTCCC
  CATTGTACTGTGGAGGAGGGTGTTCAAAAAGAGGAAAGAGAGAAGTACCGAAAGTTATTG
  GAACGACTTAAAGAAAGTGGTCATGGAAACTCTGTCTGTCCTGTAACTTCAAATTATCAC
  AGTTCTCAAAGAAGTCAGATGGACACATTAAAGACCAAAGGCTGGGGGGAAGAGCAAAAT
  CACGGAGTCAAAACAACTCAGTTTGTTCCAAAACAATATAGACTTGTTGAAACAAGGGGA
  CCTCTATGTTCATTGAGAAGTGAAAAGAGGTGTTCAAAGGGGAAAATTACTGATACAGAG
  ACGATGGTCGGAATCAGATTTGAAAATGAAAGTAGGAGGGGATACCAACTGGAGCCTGAC
  CTATCAGAAGAAGTGTCGGCCCGACTCCGCCTGGGCAGTGGAAGCAATGGCTTACTCAGG
  AGGAAAGTGTCAATAATTGAGACAAAGGAAAAGAATTGCTCAGGCAAAGAGAGGGACAGA
  AGAACGGACGATCTCCTTGAACTTACAGAGGACATGGAAAAGGAAATCAGTAATGCCCTA
  GGCCATGGCCCACAGGATGAAATCCTAAGTAGTGCTTTCAAATTGCGAATTACTCGAGGA
  GATATTCAGACATTAAAGAACTATCACTGGCTCAATGATGAAGTCATTAATTTTTACATG
  AATCTTCTGGTGGAAAGAAATAAAAAGCAAGGCTATCCAGCACTTCATGTATTCAGTACT
  TTCTTCTATCCTAAATTAAAGTCTGGGGGTTACCAAGCAGTGAAACGATGGACCAAAGGG
  GTAAATCTCTTTGAACAAGAAATTATTCTGGTGCCTATTCATCGGAAGGTACATTGGAGC
  CTGGTGGTGATTGACCTAAGAAAAAAGTGTCTTAAATATCTGGATTCTATGGGACAAAAG
  GGCCACAGGATCTGTGAGATTCTCCTTCAGTATTTACAGGATGAAAGTAAGACCAAAAGA
  AATAGTGATCTGAATCTTTTAGAGTGGACCCATCACAGCATGAAACCACACGAGATTCCT
  CAACAGCTGAATGGGAGTGATTGTGGAATGTTTACTTGTAAATATGCAGATTATATTTCT
  AGGGACAAACCTATCACATTTACTCAGCACCAGATGCCTCTCTTCCGGAAGAAGATGGTG
  TGGGAAATCCTTCATCAGCAGTTGCTGTGA
  
  Clone variation with respect to NM_021627.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021627 unedited
  NGGTTCGCATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGGGTTAAG
  ACGGCGAAGGCGGCAGCGGCGGCGACAGCTCTGGGGTTTGCGTCTCGGGGTGTGTCGGCC
  GCCGCTGCTGCTTGGGCCTGGTATGTACAGATGGCTGGTTAGGATTCTCGGCACCATTTT
  CCGTTTCTGCGACCGGTCGGTGCCCCCTGCCCGGGCCCTCCTGAAGAGGCGGCGCTCAGA
  CAGCACTCTGTTTTCTACAGTGGACACTGATGAAATACCAGCCAAAAGACCAAGATTAGA
  TTGCTTTATTCACCAAGTGAAAAACAGTCTCTACAATGCTGCCAGCTTATTTGGATTCCC
  ATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAATGTGGC
  CCCTTCAGGAGAGGTATTTTCGAACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTG
  GAACAACATGCTGAAACTGGGTAATAAATCTCCTAATGGAATAAGTGACTATCCAAAGAT
  CAGAGTGACAGTTACCCGAGATCAGCCACGCAGAGTCCTGCCTTCCTTTGGTTTTACTTT
  GAACTCAGAAGGCTGTAATAGAAGACCAGGTGGCCGTCGCCATAGCAAAGGTAATCCAGA
  GAGTTCTTTAATGTGGAAACCTCAGGAACAGGCTGTAACAGAGATGATTTCTGAAGAGAG
  TGGCCAGGGTCTGAGGCGTCCCCATTGTACTGTGGGAGAGGGTGTCCAAAAAGAGGCAAG
  AGAGAAGTACCGAAAGTTATTGCACGACTTACAGAAAGTGGCCATGGAACTCTGTCTGTC
  CTGTAACTTCCAATTATCACAGTTCTCAAAGAAGTCAGAGGGCACATTAAAGACCAAGGC
  T
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_021627 unedited
  GCCGCAATTTAGAGTCGAGTTTTTTTTTTTTTTTTTTCACAAAATAAATCCTGCATTTCC
  CACATTCATAGGGAAAAGAATCTCTTAAAAAAAATATTAGTTAGCGTTTGTTCTTGTGTG
  GGTTGAACAGTCCAAAGCTCTGAGCAGGCACAGCCTTACAAACAGGATTGCAAGCAGCCC
  TCTGCACCCCAAGTCAGGACTAGAGTACAGTGAGAGGCCTTCATGCACTTTTGACAGCTC
  AGTACCTGTGAGAACAGAAGTGATGCAGGGACTTTTTAACCCACAATGCATGAGGTATAT
  GGAAATGTCTGTGAAAGAACCACCAGCAGCTAGAGGGACCAGGCAAAGTTTTCTCACAGC
  AACTGCTGATGAAGGATTTCCCACACCATCTTCTTCCGGAAGAGAGGCATCTGGTGCTGA
  GTAAATGTGATAGGTTTGCCCCTAGAAATATAATCTGCATATTTACAAGTAAACATTCCA
  CAATCACTCCCATTCAGCTGTTGAGGAATCTCGTGTGGTTTCATGCTGTGATGGGTCCAC
  TCTAAAAGATTCAGATCACTATTTCTTTTGGTCTTACTTTCATCCTGTAAATACTGAAGG
  AGAATCTCACAGATCCTGTGGCCCTTTTGTCCCATAGAATCCACATATCTAAGACACTCT
  TTTCTTAGGTCAATCACCACCAGGCTCCAATGTACCTTCCGATGAATAGGCACCAGAATA
  ACTTCCTGTTCAAAGAGATTTCCCCCTTTGGCCCATCGTTTCACTGCTTGGAACCCCCAG
  ACTTTTATTAGGATAGAAGAAAGTCTGAATACTGAATGCTGGATAGCCTGCTTTTATCTC
  TCCACCAGAGATCATGTAAACATATGCACTCTCACTGGCCAGGAAGGTCTTAAGCCGGAA
  TTCTCCCAGAATTCCATTGAAGCCCACTAGATTATCCCTGGGCAGGGCAAGGCATACGGA
  TCCTTCCAGCCCCGAAN
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_021627
• Insert Size: 2100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_021627.2, NP_067640.2
• RefSeq Size: 3207 bp
• RefSeq ORF: 1770 bp
• Locus ID: 59343
• UniProt ID: Q9HC62
• Cytogenetics: 3q27.2
• Domains: Peptidase_C48
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Wnt signaling pathway
• Gene Summary: SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM, Apr 2004]