ACKR3 (NM_020311) Human Untagged Clone

CAT#: SC112665

CXCR7 (untagged)-Human chemokine (C-X-C motif) receptor 7 (CXCR7)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACKR3
• Synonyms: CMKOR1; CXC-R7; CXCR-7; CXCR7; GPR159; RDC-1; RDC1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112665 sequence for NM_020311 edited (data generated by NextGen Sequencing)
  ATGGATCTGCATCTCTTCGACTACTCAGAGCCAGGGAACTTCTCGGACATCAGCTGGCCA
  TGCAACAGCAGCGACTGCATCGTGGTGGACACGGTGATGTGTCCCAACATGCCCAACAAA
  AGCGTCCTGCTCTACACGCTCTCCTTCATTTACATTTTCATTTTCGTCATCGGCATGATT
  GCCAACTCCGTGGTGGTCTGGGTGAATATCCAGGCCAAGACCACAGGCTATGACACGCAC
  TGCTACATCTTGAACCTGGCCATTGCCGACCTGTGGGTTGTCCTCACCATCCCAGTCTGG
  GTGGTCAGTCTCGTGCAGCACAACCAGTGGCCCATGGGCGAGCTCACGTGCAAAGTCACA
  CACCTCATCTTCTCCATCAACCTCTTCGGCAGCATTTTCTTCCTCACGTGCATGAGCGTG
  GACCGCTACCTCTCCATCACCTACTTCACCAACACCCCCAGCAGCAGGAAGAAGATGGTA
  CGCCGTGTCGTCTGCATCCTGGTGTGGCTGCTGGCCTTCTGCGTGTCTCTGCCTGACACC
  TACTACCTGAAGACCGTCACGTCTGCGTCCAACAATGAGACCTACTGCCGGTCCTTCTAC
  CCCGAGCACAGCATCAAGGAGTGGCTGATCGGCATGGAGCTGGTCTCCGTTGTCTTGGGC
  TTTGCCGTTCCCTTCTCCATTATCGCTGTCTTCTACTTCCTGCTGGCCAGAGCCATCTCG
  GCGTCCAGTGACCAGGAGAAGCACAGCAGCCGGAAGATCATCTTCTCCTACGTGGTGGTC
  TTCCTTGTCTGCTGGCTGCCCTACCACGTGGCGGTGCTGCTGGACATCTTCTCCATCCTG
  CACTACATCCCTTTCACCTGCCGGCTGGAGCACGCCCTCTTCACGGCCCTGCATGTCACA
  CAGTGCCTGTCGCTGGTGCACTGCTGCGTCAACCCTGTCCTCTACAGCTTCATCAATCGC
  AACTACAGGTACGAGCTGATGAAGGCCTTCATCTTCAAGTACTCGGCCAAAACAGGGCTC
  ACCAAGCTCATCGATGCCTCCAGAGTCTCAGAGACGGAGTACTCTGCCTTGGAGCAGAGC
  ACCAAATGA
  
  Clone variation with respect to NM_020311.2
  162 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020311 unedited
  NTTGTCAAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGAAGGGAG
  CCAGCGCACAGCACAGCCAGGAAGGCGAGCGAGCCCAGCCAGCCCAGCCAGCCCAGCCAG
  CCCGGAGGTCATTTGATTGCCCGCCTCAGAACGATGGATCTGCATCTCTTCGACTACTCA
  GAGCCAGGGAACTTCTCGGACATCAGCTGGCCATGCAACAGCAGCGACTGCATCGTGGTG
  GACACGGTGATGTGTCCCAACATGCCCAACAAAAGCGTCCTGCTCTACACGCTCTCCTTC
  ATTTACATTTTCATTTTCGTCATCGGCATGATTGCCAACTCCGTGGTGGTCTGGGTGAAT
  ATCCAGGCCAAGACCACAGGCTATGACACGCACTGCTACATCTTGAACCTGGCCATTGCC
  GACCTGTGGGTTGTCCTCACCATCCCAGTCTGGGTGGTCAGTCTCGTGCAGCACAACCAG
  TGGCCCATGGGCGAGCTCACGTGCAAAGTCACACACCTCATCTTCTCCATCAACCTCTTC
  GGCAGCATTTTCTTCCTCACGTGCATGAGCGTGGACCGCTACCTCTCCATCACCTACTTC
  ACCAACACCCCCAGCAGCAGGAAGAAGATGGTACGCCGTGTCGTCTGCATCCTGGTGTGG
  CTGCTGGCCTTCTGCGTGTCTCTGCCTGACACCTACTACCTGAAGACCGTCACGTCTGCG
  TCCAACAATGAGACCTACTGCCGGTCCTTCTACCCCGAGCACAGCATCAAGGAGTGGCTG
  ATCGGCATGGAGCTGGTCTNCGTTGTCTTGGGCTNTGCCGTTCCCTTCTNCTTATCGCTG
  TCTTCTACTTNCTGCTGGCCAGAGCCATCTCGCGTCCAGTGACCCAGAGAGCACAGCAGC
  CGGAGACATCTCNTCTACGTGGTGGGCTTCCTTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020311 unedited
  CCTTTTTAACTATGNACCGCGGCNCGTATTCTCATGATCGGTCCTTTTTTTTTTTTTTTT
  AGGAAACAAAAATTTTTATTAAAAAACTTCACTTACACATTGCGTAGAATATCTGAAATG
  CAACTGCTCGTTGCGTGTGCAGATCCGTAGTTTCAGCAACAGCCCCCCCCGCGATCGCTA
  AATGTACCTTTACACTACTATTAATGTGACAAACTGCATTACACAGCAGTTCTCGCTTCA
  TATCCCGCGCCGGTACAACCCACCACACATCTTTTCAACCATGGTCCATAACACATCGCA
  GCCTCCCACTGCTATCCATCTCCCTCCTCCCTTACTCCCACTCCTACCTCCTTGTTCCCC
  TCCTCTCTCGTCTCTGTCATTCTTCCCCCCATTTCCACGTTTTGCCCACCCTCAAAACCA
  CACCCACTCTGAATATATGCTAGCATTTATGTCTGTGTTACAATACCCACCATATAGTTA
  CACCCCCCACTCCTCTCACCAGGCCCACCTATTCTGCATAACTACCGCGCTCATCCCTAC
  TCCCTTCGCCCCTCGCCAATCCTTTGCCCCCTTGACTTCCCCACCTTCCCGTATCTTCAG
  TTTTCGTCTGCCCTCCCCCTCGCCTCTGACTCATTTTCTTGTCGGTGTACCCAAGCGCCG
  ACTGCCGATAACCTGTCGCGCCGTTAAGTCCAATGTAAGCCTGGGCCCTTCCAAAACGTA
  AGTACGTTCGCACCCCCCCCCCGTCGCCCTTACCTTCACGCGGCCTGAACTATGGGGGCA
  CTTCGTTTGTCTTATTCCCCCCCGGCTTCTTCCGTGCTTGTACCCAACCATACTTTCCTT
  TATTTTCTTTCGCATTACCATCCGGGGCCTGTTCCAGTTTCCACCCCCCTCCTTTCAACC
  TGTAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020311
• Insert Size: 2090 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_020311.1, NP_064707.1
• RefSeq Size: 2064 bp
• RefSeq ORF: 1089 bp
• Locus ID: 57007
• UniProt ID: P25106
• Cytogenetics: 2q37.3
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Gene Summary: This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]