Sigma1 receptor (SIGMAR1) (NM_005866) Human Untagged Clone

CAT#: SC111748

SIGMAR1 (untagged)-Human sigma non-opioid intracellular receptor 1 (SIGMAR1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Sigma1 receptor
• Synonyms: ALS16; DSMA2; hSigmaR1; OPRS1; SIG-1R; sigma1R; SR-BP; SR-BP1; SRBP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005866, RT-PCR generated
  ATGCCGTGGGCCGTGGGCCGGCGGTGGGCGTGGGCCGCGCTGCTCCTGGCTGTCGCAGCG
  GTGCTGACCCAGGTCGTCTGGCTCTGGCTGGGTACGCAGAGCTTCGTCTTCCAGCGCGAA
  GAGATAGCGCAGTTGGCGCGGCAGTACGCTGGGCTGGACCACGAGCTGGCCTTCTCTCGT
  CTGATCGTGGAGCTGCGGCGGCTGCACCCAGGCCACGTGCTGCCCGACGAGGAGCTGCAG
  TGGGTGTTCGTGAATGCGGGTGGCTGGATGGGCGCCATGTGCCTTCTGCACGCCTCGCTG
  TCCGAGTATGTGCTGCTCTTCGGCACCGCCTTGGGCTCCCGCGGCCACTCGGGGCGCTAC
  TGGGCTGAGATCTCGGATACCATCATCTCTGGCACCTTCCACCAGTGGAGAGAGGGCACC
  ACCAAAAGTGAGGTCTTCTACCCAGGGGAGACGGTAGTACACGGGCCTGGTGAGGCAACA
  GCTGTGGAGTGGGGGCCAAACACATGGATGGTGGAGTACGGCCGGGGCGTCATCCCATCC
  ACCCTGGCCTTCGCGCTGGCCGACACTGTCTTCAGCACCCAGGACTTCCTCACCCTCTTC
  TATACTCTTCGCTCCTATGCTCGGGGCCTCCGGCTTGAGCTCACCACCTACCTCTTTGGC
  CAGGACCCTTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005866 unedited
  GGCGAGCCTACAGTATTTGTAAACGACTCACGTCTGGCGGCCGCCACGTGTGATGGAATC
  TGCAGAATCGGCTTATGCCGTGGGCCGTGGGCCGGCGGTGGGCGTGGGCCGCGCTGCTCC
  TGGCTGTCGCAGCGGTGCTGACCCAGGTCGTCTGGCTCTGGCTGGGTACGCAGAGCTTCG
  TCTTCCAGCGCGAAGAGATAGCGCAGTTGGCGCGGTAGTACGCTGGGCTGGACCACGAGC
  TGGCGCTTCTCTCGTCTGATCGTGGAGCTGCGGCGGCTGCACCCAGGCCACGTGCTGCCC
  GACGAGGAGCTGCAATGGGTGTTCGTGAATGCGGGTGGCTGGATGGGCGCCATGTGCCTT
  CTGCACGCCTCGCTGTCCGAGTATGTGCTGCTCTTCGGCACCGCCTTGGGCTCCCGCGGC
  CACTCGGGGCGCTACTGGGCTGAGATCTCGGATACCATCATCTCTGGCACCTTCCACCAG
  TGGAGAGAGGGCACCACCAAAAGTGAGGTCTTCTACCCAGGGGAGACGGTAGTACACGGG
  CCTGGTGAGGCAACAGCTGTGGAGTGGGGGCCAAACACATGGATGGTGGAGTACGGCCGG
  GGCGTCATCCCATCCACCCTGGCCTTTGGGCTGGCCGACACTGTCTTCAGCACCCAGGAC
  TTCCTCACCCTCTTCTATACTCTTCGCTCCTATGCTCGGGGGCCTCCCGGCTGGAGCTCA
  CCACCTACCTCTTTGGCCAGGACCTTTGACCAGCCCAGAACCGAATTCCAACACAGTGGC
  GGCCGTTACTAGTGGGACCCGAGCTCTGTGCCCGATATCAAAGCTGGGCGACTCTAGATT
  GCGGCCCCGGTCATACCTGTTTTCTGGACAGATCCCGGGGTGCAATA
  
• Restriction Sites: Please inquire
• ACCN: NM_005866
• Insert Size: 1700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005866.2, NP_005857.1
• RefSeq Size: 1655 bp
• RefSeq ORF: 672 bp
• Locus ID: 10280
• UniProt ID: Q99720
• Cytogenetics: 9p13.3
• Domains: ERG2_Sigma1R
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Gene Summary: This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2013]
  Transcript Variant: This variant (1) encodes the longest isoform (1).