P2Y6 (P2RY6) (NM_176797) Human Untagged Clone

CAT#: SC109534

P2RY6 (untagged)-Human pyrimidinergic receptor P2Y, G-protein coupled, 6 (P2RY6), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: P2Y6
• Synonyms: P2Y6
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC109534 sequence for NM_176797 edited (data generated by NextGen Sequencing)
  ATGGAATGGGACAATGGCACAGGCCAGGCTCTGGGCTTGCCACCCACCACCTGTGTCTAC
  CGCGAGAACTTCAAGCAACTGCTGCTGCCACCTGTGTATTCGGCGGTGCTGGCGGCTGGC
  CTGCCGCTGAACATCTGTGTCATTACCCAGATCTGCACGTCCCGCCGGGCCCTGACCCGC
  ACGGCCGTGTACACCCTAAACCTTGCTCTGGCTGACCTGCTATATGCCTGCTCCCTGCCC
  CTGCTCATCTACAACTATGCCCAAGGTGATCACTGGCCCTTTGGCGACTTCGCCTGCCGC
  CTGGTCCGCTTCCTCTTCTATGCCAACCTGCACGGCAGCATCCTCTTCCTCACCTGCATC
  AGCTTCCAGCGCTACCTGGGCATCTGCCACCCGCTGGCCCCCTGGCACAAACGTGGGGGC
  CGCCGGGCTGCCTGGCTAGTGTGTGTAGCCGTGTGGCTGGCCGTGACAACCCAGTGCCTG
  CCCACAGCCATCTTCGCTGCCACAGGCATCCAGCGTAACCGCACTGTCTGCTATGACCTC
  AGCCCGCCTGCCCTGGCCACCCACTATATGCCCTATGGCATGGCTCTCACTGTCATCGGC
  TTCCTGCTGCCCTTTGCTGCCCTGCTGGCCTGCTACTGTCTCCTGGCCTGCCGCCTGTGC
  CGCCAGGATGGCCCGGCAGAGCCTGTGGCCCAGGAGCGGCGTGGCAAGGCGGCCCGCATG
  GCCGTGGTGGTGGCTGCTGCCTTTGCCATCAGCTTCCTGCCTTTTCACATCACCAAGACA
  GCCTACCTGGCAGTGCGCTCGACGCCGGGCGTCCCCTGCACTGTATTGGAGGCCTTTGCA
  GCGGCCTACAAAGGCACGCGGCCGTTTGCCAGTGCCAACAGCGTGCTGGACCCCATCCTC
  TTCTACTTCACCCAGAAGAAGTTCCGCCGGCGACCACATGAGCTCCTACAGAAACTCACA
  GCCAAATGGCAGAGGCAGGGTCGCTGA
  
  Clone variation with respect to NM_176797.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_176797 unedited
  GCACGAGGACAGTTTCAGGCACANAACTGACTGGCAGCAGGGGCTGCTCCACGAGTGGGA
  ATTTGCTCCAGCACTTCACGGACTGCAAGCGAGGCACTTGCTAACTCTTGGCCTCCCTGA
  ACATAGGAAACCCACCTGGGCAGCCATGGAATGGGACAATGGCACAGGCCAGGCTCTGGG
  CTTGCCACCCACCACCTGTGTCTACCGCGAGAACTTCAAGCAACTGCTGCTGCCACCTGT
  GTATTCGGCGGTGCTGGCGGCTGGCCTGCCGCTGAACATCTGTGTCATTACCCAGATCTG
  CACGTCCCGCCGGGCCCTGACCCGCACGGCCGTGTACACCCTAAACCTTGCTCTGGCTGA
  CCTGCTATATGCCTGCTCCCTGCCCCTGCTCATCTACAACTATGCCCAAGGTGATCACTG
  GCCCTTTGGCGACTTCGCCTGCCGCCTGGTCCGCTTCCTCTTCTATGCCAACCTGCACGG
  CAGCATCCTCTTCCTCACCTGCATCAGCTTCCAGCGCTACCTGGGCATCTGCCACCCGCT
  GGCCCCCTGGCACAAACGTGGGGGCCGCCGGGCTGCCTGGCTAGTGTGTGTAGCCGTGTG
  GCTGGCCGTGACAACCCAGTGCCTGCCCACAGCCATCTTCGCTGCCACAGGCATCCAGCG
  TAACCGCACTGTCTGCTATGACCTCAGCCCGCCTGCCCTGGCCACCCACTATATGCCCTA
  TGGCATGGCTCTCACTGTCATCGGCTTCCTGCTGCCCTTTGCTGCCCTGCTGGCCTGCTA
  CTGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_176797 unedited
  NNCCAGGNGANGAGCACTGGGGNAGGGGCTCACAGGGCATGCCACCCGGGTTCTGTTCAG
  GAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTTTT
  TTTTGACAGTACACGTCACACTGTATTTTTGTGAGCACCTTAATGTGGTTTCCCCAGCTC
  TCCATGGCTGACTGGGACCTCTCAAGAGCCAGGCCCAGGTCTGTCCATCTCCATGCCCAC
  AGGGTCTGGGCCAGAGAAGGGGCTGAAAAAATAGTTTTTGGTGAGCTTCTGGGTCCTGTG
  AGGGATCTTAACTCCATGCCCAGCTGAGCTGAACTCTAATTCTCCGCATGGTTTGGGGTG
  TGGTGGGGCTCCTGGTGCCCCGGACACAATGGCAAATATGAAGGCTGCCCAGGACCTGGA
  GGACTCAGCGACCCTGCCTCTGCCATTTGGCTGTGAGTTTCTGGANGAGCTCATGTGGTC
  GCCGGCGGAACTTCTTCTGGGTGAAGTATAAGAGGATGGGGTCCAGCACACTTTTGGCAC
  TGGATAACGGCCCCCTGCCTTTTTATGCCGCTGCAAAAGCCTTCAAATCTGTGGCAGGGG
  AACCCTTGAGTCAAACCCCACGCCAGGGACGCGTGGCTATGGGACGTTAAGAGGAAAGAA
  CCCTTGAGGTAAGAGGCACGACGCACCCCCATGGGTTAGGCTAAGCGACGCGACACAAAC
  TATATCTGGACGCCGCGTCGTAGCGAGCCCGCCGGGCCCCCTACGTTTTTTGTATGAACG
  CACCGCTCAACCAATGGACGGAGAGATCGAGCAGCGGAAGAGGTACGACGCCCGCGCGTA
  TTATAGAAGAATCCAACGCCGGCGTCTAGTGCCACCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_176797
• Insert Size: 1650 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_176797.1, NP_789767.1
• RefSeq Size: 1555 bp
• RefSeq ORF: 987 bp
• Locus ID: 5031
• UniProt ID: Q15077
• Cytogenetics: 11q13.4
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Mar 2013]
  Transcript Variant: This variant (1) represents the shortest transcript. Variants 1,2,3,5,6,7, and 8 encode the same isoform (1).