PVRIG (NM_024070) Human Untagged Clone

CAT#: SC108878

PVRIG (untagged)-Human poliovirus receptor related immunoglobulin domain containing (PVRIG)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PVRIG
• Synonyms: C7orf15; CD112R
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_024070, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGAACAGAGGCACAGGTGCCGGCCCTGCAGCCCCCAGAACCTGGACTGGAGGGGGCCATGGGGCACC
  GGACCCTGGTCCTGCCCTGGGTGCTGCTGACCTTGTGTGTCACTGCGGGGACCCCGGAGGTGTGGGTTCA
  AGTTCGGATGGAGGCCACCGAGCTCTCGTCCTTCACCATCCGTTGTGGGTTCCTGGGGTCTGGCTCCATC
  TCCCTGGTGACTGTGAGCTGGGGGGGCCCCAACGGTGCTGGGGGGACCACGCTGGCTGTGTTGCACCCAG
  AACGTGGCATCCGGCAATGGGCCCCTGCTCGCCAGGCCCGCTGGGAAACCCAGAGCAGCATCTCTCTCAT
  CCTGGAAGGCTCTGGGGCCAGCAGCCCCTGCGCCAACACCACCTTCTGCTGCAAGTTTGCGTCCTTCCCT
  GAGGGCTCCTGGGAGGCCTGTGGGAGCCTCCCGCCCAGCTCAGACCCAGGGCTCTCTGCCCCGCCGACTC
  CTGCCCCCATTCTGCGGGCAGACCTGGCCGGGATCTTGGGGGTCTCAGGAGTCCTCCTCTTTGGCTGTGT
  CTACCTCCTTCATCTGCTGCGCCGACATAAGCACCGCCCTGCCCCTAGGCTCCAGCCGTCCCGCACCAGC
  CCCCAGGCACCGAGAGCACGAGCATGGGCACCAAGCCAGGCCTCCCAGGCTGCTCTTCACGTCCCTTATG
  CCACTATCAACACCAGCTGCCGCCCAGCTACTTTGGACACAGCTCACCCCCATGGGGGGCCGTCCTGGTG
  GGCGTCACTCCCCACCCACGCTGCACACCGGCCCCAGGGCCCTGCCGCCTGGGCCTCCACACCCATCCCT
  GCACGTGGCAGCTTTGTCTCTGTTGAGAATGGACTCTACGCTCAGGCAGGGGAGAGGCCTCCTCACACTG
  GTCCCGGCCTCACTCTTTTCCCTGACCCTCGGGGGCCCAGGGCCATGGAAGGACCCTTAGGAGTTCGATG
  A
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_024070 unedited
  GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTTTAAGCGTGGGACCC
  ACGTCAGATTGGTGGTGGGTCATGCATGCTGGGGTGGCTCTCAGGTCCTCCCTGCTGGCT
  TCCCACTCCCAGGGGCTTTCTCCTCCCAGATTCCTTAGCTGGGTGAGGGGCAGGACAGAG
  CCCTTTCCTAGGGAAGCCCGGCACCCCCTGCTGTCCAGGGAAGGGGAGTCCTTCTAGCCC
  CTGACAGCTTCTCTGCCCCTCCCCTGGCCTCCCCAGGCCTAGCCAGGGTTGAGTTCTCAC
  CCACCTGTGCCGCCCTGCCTTGTTACCTGGAAGCACAGCCTTGGGGACTGAGCAGGCCCT
  CACTGTCACTTTAAGAAGGGAATCAGCCACTTTGTGCTCACCACCTCTGGGGAAGGTGTG
  AGAGGAGAGAAGGAAGTGGCTGTTTGGCTGCTGACAACATGAAGACTTCCTGCGATGAGA
  ACAGAGGCACAGGTGCCGGCCCTGCAGCCCCCAGAACCCGGACTGGAGGGGGCCATGGGG
  CGCCGGACCCTGGCCCTGCCCTGGGTGCTGCTGACCCTGCGTGTCACTGCAGGGACCCCG
  GAGGTGTGAGTACAAGTTCGGATGGAGGCCACCGAGCTCTCGTCCTTCACCATCCGTTGT
  GGGTTCCTGGAGTCTGCCTCCATCTCCCTGTTGACTGTGAGCCAGGGGGGGCCCCGATGG
  TGCTGGGGGGGACCACGCTGGCTGTGCTGCACCCCGAACTTGGCATCCACCATGGGCCCC
  CTGCTCGCCAGGCCCGCCTGGGAACCCCANACCGCATCTCTCTCATCCTGGAAGGCCTCG
  GGGNCAACAGCCCCTGCGCCACCCCACCTTTGCTTGNAGTTTGCGTCCTTCCCTGGGCCC
  TCTGGAGGCCTGGGGAGCCCTCCGCCACTCAACCAGGGGGGCGGGTGGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_024070
• Insert Size: 2750 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_024070.3, NP_076975.2
• RefSeq Size: 1587 bp
• RefSeq ORF: 981 bp
• Locus ID: 79037
• UniProt ID: Q6DKI7
• Cytogenetics: 7q22.1
• Protein Families: Transmembrane
• Gene Summary: Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.[UniProtKB/Swiss-Prot Function]